Protein Alignment unc-4 and pb

DIOPT Version :10

• Sequence 1: NP_573242.2
• Gene: unc-4 / 32757
• FlyBaseID: FBgn0024184
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Alignment Length: 690
• Identity: 139/690 - (20%)
• Similarity: 207/690 - (30%)
• Gaps: 228/690 - (33%)

  Fly    43 EETGRSSSTSSNSIPNAHRTNAGQHLLGGSPSSACSTSVSGCGMPSEGLHPTAALQLYAAAAQLA 107
            :.|...:...|.|..|..:...||          .|..|.|||               .|.....
  Fly     9 DTTSMGTQIKSESPLNPLQVQTGQ----------TSLPVGGCG---------------GAGVVGG 48

  Fly   108 PNGVRVPPWGPFL-QFGVPGVFGPNGPFLGR--PRFD----------AASAGGHPNSAAAAA--- 156
            ..||.|....|.: |.|||.|  |:...:.:  |..|          .||.||..||..:.|
  Fly    49 VGGVGVSVGQPGIGQQGVPPV--PSVLMVNKMTPNCDKRSADTAYWMTASEGGFINSQPSMAEFL 111

  Fly   157 --AATQMAAVNASNAFANLTGLSAAALRNVSAAQTTAVAAVASTV----ATIQHRLMIGNRQSLP 215
              .:.:...:........:.|:......||.......|..|..|.    :..::..|...:.|..
  Fly   112 NHLSPESPKIGTPVGSGAIGGVGVNVNVNVGVGVGYPVGVVPQTPDGMDSVPEYPWMKEKKTSRK 176

  Fly   216 PAGPPSEGSNE------DGGFPGDGDDDSSAAKRRRSRTNFNSWQLEELERAFSASHYPDIFMRE 274
            .:...::|.|.      :.|.|            ||.||.:.:.||.|||:.|..:.|.....|.
  Fly   177 SSNNNNQGDNSITEFVPENGLP------------RRLRTAYTNTQLLELEKEFHFNKYLCRPRRI 229

  Fly   275 ALAMRLDLKESRVAVWFQNRRAKVRKREHTK----------KGPG--RPAHNAQPQTCSGEPIP- 326
            .:|..|||.|.:|.|||||||.|.:::..:|          ||..  ..:::...::|.|..:|
  Fly   230 EIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSCQGCELPS 294

  Fly   327 ---PNELKAKERARRRKKLAKAIDRQARKLQAK-----GITVDL------EALKAEYISQHKANG 377
               |:..............|...:..|..|...     ||:.:|      .|..........|:.
  Fly   295 DDIPDSTSNSRGHNNNTPSATNNNPSAGNLTPNSSLETGISSNLMGSTTVSASNVISADSSVASS 359

  Fly   378 TFSDSDLE----------DDG--IQIDVVGGT--------------------DSDDEGDSDAVSP 410
            ...|.|:|          |||  |:.:.|..:                    |||.....:|.:.
  Fly   360 VSLDEDIEESSPIKVKKKDDGQVIKKEAVSTSSKASPFGYENSTPSLVSFRRDSDASAVGNAPTS 424

  Fly   411 VRLG-----------------GGGGGGGGTGGGGGGGASSSLHCGLDGDGDSSRAGSFIGGGGSL 458
            ..:|                 .....|.|:|||..||.....:
  Fly   425 KAVGKKRFQSAANAIATPTPLSDSNSGNGSGGGPAGGYFPGYY---------------------- 467

  Fly   459 GSPSSVAPPSMLSNGAVQFGKLEPMD---------------------------GNESEERDRERD 496
                    ||......||..:|.|..                           .|:.:....|..
  Fly   468 --------PSPKQQQQVQQQQLHPQQQQLPQQQPQDYYGKYDIEFAASPHHNPHNKQQALHGEYL 524

  Fly   497 SPKPLLFPAKAFHQLNLQSSQQHHGLVVGQGQGSGSGH-GHGHQHNHH-------QHHLHH---- 549
            ||||   .:..||| |.|..||:..........:|:.: .|..||:||       |||.:|
  Fly   525 SPKP---SSANFHQ-NSQQQQQNDHFYYNYNDTNGTPYLNHQQQHHHHAQHHQQQQHHQNHVADF 585

  Fly   550 -----GSASASAAAAVANL-------VHQTSPISMRRSNP 577
                 |.::.:..|...|:       .||...:..::..|
  Fly   586 EGPVNGPSNFNNGAYYDNMSFQQQAQAHQHQTVVFQQQQP 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-4	NP_573242.2	Homeodomain	244..300	CDD:459649	26/55 (47%)
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	26/55 (47%)