Protein Alignment unc-4 and en

DIOPT Version :10

• Sequence 1: NP_573242.2
• Gene: unc-4 / 32757
• FlyBaseID: FBgn0024184
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Alignment Length: 362
• Identity: 79/362 - (21%)
• Similarity: 130/362 - (35%)
• Gaps: 100/362 - (27%)

  Fly    42 PEETGRSSSTSSNSIPNAHRTNAGQHLLGGSPSSACSTSVSGCGMPSEG------LHPTAALQLY 100
            |.|..||.:.:.::....       .||..|.....:.:.:...|..|.      .:|.|..:::
  Fly   204 PFEASRSQTATPSAFTRV-------DLLEFSRQQQAAAAAATAAMMLERANFLNCFNPAAYPRIH 261

  Fly   101 AAAAQ-----LAPNGVRVPPWGPFLQFGVP--GVFG-----------PNGPFLGRPRFDAAS--- 144
            ....|     .|.|.|..||....:....|  ...|           |..|.:.:|...:::
  Fly   262 EEIVQSRLRRSAANAVIPPPMSSKMSDANPEKSALGSLCKAVSQIGQPAAPTMTQPPLSSSASSL 326

  Fly   145 AGGHPNSAAAAAAATQMAAVNASNAFANLTGLSAAALRNVSAAQTTAVAAVASTVATIQHRLMIG 209
            |...|.|.|:..::|...|.::|   ::.:|.|:|| .:::::.::.:.|..|           |
  Fly   327 ASPPPASNASTISSTSSVATSSS---SSSSGCSSAA-SSLNSSPSSRLGASGS-----------G 376

  Fly   210 NRQSLP---PAGPPSEGSNEDGGFPGD----------------------------GDDDSSAAKR 243
            ...|.|   |..|||..|.:.|....|                            .|..||..:.
  Fly   377 VNASSPQPQPIPPPSAVSRDSGMESSDDTRSETGSTTTEGGKNEMWPAWVYCTRYSDRPSSGPRY 441

  Fly   244 R-------------RSRTNFNSWQLEELERAFSASHYPDIFMREALAMRLDLKESRVAVWFQNRR 295
            |             |.||.|:|.||..|:|.|:.:.|.....|:.|:..|.|.|:::.:||||:|
  Fly   442 RRPKQPKDKTNDEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKR 506

  Fly   296 AKVRKREHTKK-------GPGRPAHNAQPQTCSGEPI 325
            ||::|...:|.       ..|...|...|.|...|.:
  Fly   507 AKIKKSTGSKNPLALQLMAQGLYNHTTVPLTKEEEEL 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-4	NP_573242.2	Homeodomain	244..300	CDD:459649	24/68 (35%)
en	NP_523700.2	Homeodomain	455..511	CDD:459649	23/55 (42%)
		Engrail_1_C_sig	512..542	CDD:431338	5/29 (17%)