Protein Alignment unc-4 and prd

DIOPT Version :9

• Sequence 1: NP_001285389.1
• Gene: unc-4 / 32757
• FlyBaseID: FBgn0024184
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_723721.1
• Gene: prd / 34629
• FlyBaseID: FBgn0003145
• Length: 613
• Species: Drosophila melanogaster
• Alignment Length: 546
• Identity: 128/546 - (23%)
• Similarity: 191/546 - (34%)
• Gaps: 170/546 - (31%)

  Fly   125 PGVFGPNGPFLGRPRFDAASAGGHPNSAAAAAAATQMAAVNASNAFANLTGLSAAALRNVSAAQT 189
            |||.|.:.|.:..|..:                 .::.....|:     .|:.:..:|.....:.
  Fly    91 PGVIGGSKPRIATPEIE-----------------NRIEEYKRSS-----PGMFSWEIREKLIREG 133

  Fly   190 TAVAAVASTVATIQHRLMIGNRQSL---------PPAGPPSE-----GSNEDGGFPGDG---DDD 237
            ....:.|.:|:.|. ||:.|....|         .|||..::     ||:..||...:|   |:|
  Fly   134 VCDRSTAPSVSAIS-RLVRGRDAPLDNDMSSASGSPAGDGTKASSSCGSDVSGGHHNNGKPSDED 197

  Fly   238 SS----------AAKRRRSRTNFNSWQLEELERAFSASHYPDIFMREALAMRLDLKESRVAVWFQ 292
            .|          ..|:||.||.|::.||:||||||..:.||||:.||.||.|.:|.|:|:.|||.
  Fly   198 ISDCESEPGIALKRKQRRCRTTFSASQLDELERAFERTQYPDIYTREELAQRTNLTEARIQVWFS 262

  Fly   293 NRRAKVRKREHTKKGPGRP-----------AHNAQPQTCSGEP------IPPNELKAKERARRRK 340
            ||||::|| :||....|.|           |.::.|...|..|      :.|..|......:::.
  Fly   263 NRRARLRK-QHTSVSGGAPGGAAASVSHVAASSSLPSVVSSVPSMAPLAMMPGSLDPATVYQQQY 326

  Fly   341 KL--------AKAIDRQARKLQAKGITV---------DLEALKAEYISQHKANGTFSDSDL--ED 386
            ..        ..|....|....:.|||.         :..|..|.||...:...|....::  ..
  Fly   327 DFYGSHANISVSAAAPMASSNLSPGITTTPPHHHQFYNPSANTASYIMPGENGNTTPTGNIIVSS 391

  Fly   387 DGIQIDVVGGTDSD-------DEGDSDAVS---------PVRLG---GGGGGGGGTGGGGGGGAS 432
            ...|:..|.||:::       :|..:::||         |..|.   .|.|....:|...|...|
  Fly   392 YETQLGSVYGTETETHQTMPRNESPNESVSSAFGQLPPTPNSLSAVVSGAGVTSSSGANSGADPS 456

  Fly   433 SSLHCGLDGDGDSSRA-------------GSFIGGGGSLGSPSSVAPPSMLSNGAVQFGKLEPMD 484
            .||.....|..:.|.|             ....||..|:.:....||             |.|.|
  Fly   457 QSLANASAGSEELSAALKVESVDLIAASQSQLYGGWSSMQALRPNAP-------------LSPED 508

  Fly   485 G-NESEERDRERD------------SPKPLLFPAKAFHQLNLQSSQQHHGLVVGQGQGSGSGHGH 536
            . |.:....:..|            :|:...:||..       .:..||            ||.|
  Fly   509 SLNSTSSTSQALDVTAHQMFHPYQHTPQYASYPAPG-------HAHSHH------------GHPH 554

  Fly   537 G---HQHNHHQH---HLHHGSASASA 556
            .   |.|.|.|:   |.|:...|:||
  Fly   555 APHPHAHPHPQYAGAHPHYPPPSSSA 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-4	NP_001285389.1	Homeobox	246..299	CDD:278475	30/52 (58%)
		NK	<327..>368	CDD:302627	8/57 (14%)
prd	NP_723721.1	PAX	27..154	CDD:238076	15/85 (18%)
		Homeobox	217..269	CDD:278475	30/51 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450916
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840