Protein Alignment unc-4 and Alx4

DIOPT Version :10

• Sequence 1: NP_573242.2
• Gene: unc-4 / 32757
• FlyBaseID: FBgn0024184
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_031468.1
• Gene: Alx4 / 11695
• MGIID: 108359
• Length: 399
• Species: Mus musculus
• Alignment Length: 296
• Identity: 90/296 - (30%)
• Similarity: 116/296 - (39%)
• Gaps: 75/296 - (25%)

  Fly    44 ETGRSSSTSSNSIPNAHRTNAGQHLLGGSP------SSACSTSVSGCGMPSEGLHPTAALQLYAA 102
            ||..|...|..:..:|:.:...|...|.||      .....|:....|...:|.....:...|.|
Mouse     4 ETCVSYCESPAAAMDAYYSPVSQSREGSSPFRGFPGGDKFGTTFLSAGAKGQGFGDAKSRARYGA 68

  Fly   103 AAQ--LAP----NGVR-----------------VPPWGP---FLQFG---VPGVFGPNGPFLGRP 138
            ..|  .||    :|.|                 .||..|   :||.|   .|    |:|..
Mouse    69 GQQDLAAPLESSSGARGSFNKFQPQPPTPQPPPAPPAPPAHLYLQRGACKTP----PDGSL---- 125

  Fly   139 RFDAASAGGHPNSAAAAAAATQMAAVNASNAFANLTGLSAAALRNVS--AAQTTAVAAVASTVAT 201
            :....| |||       .||.|:.      .:|..:.|....|...|  .....:..:|..|.|
Mouse   126 KLQEGS-GGH-------NAALQVP------CYAKESNLGEPELPPDSEPVGMDNSYLSVKETGA- 175

  Fly   202 IQHRLMIGNRQSLPPAGPPSEGSNEDGGFPGDGDDDSSAAKRRRSRTNFNSWQLEELERAFSASH 266
                           .||....|.|........|.:|:..|:||:||.|.|:||||||:.|..:|
Mouse   176 ---------------KGPQDRASAEIPSPLEKTDSESNKGKKRRNRTTFTSYQLEELEKVFQKTH 225

  Fly   267 YPDIFMREALAMRLDLKESRVAVWFQNRRAKVRKRE 302
            |||::.||.||||.||.|:||.|||||||||.||||
Mouse   226 YPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRE 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-4	NP_573242.2	Homeodomain	244..300	CDD:459649	37/55 (67%)
Alx4	NP_031468.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	68..133		16/73 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..206		11/50 (22%)
		Homeodomain	203..259	CDD:459649	37/55 (67%)
		OAR	375..393	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	379..392