Protein Alignment unc-4 and Vsx1

DIOPT Version :10

• Sequence 1: NP_573242.2
• Gene: unc-4 / 32757
• FlyBaseID: FBgn0024184
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: NP_473409.1
• Gene: Vsx1 / 114889
• MGIID: 1890816
• Length: 363
• Species: Mus musculus
• Alignment Length: 271
• Identity: 82/271 - (30%)
• Similarity: 115/271 - (42%)
• Gaps: 65/271 - (23%)

  Fly   106 LAPNGVRVPPWGPFLQ-FGVPGVFG-------PNGPFL----GRPRFDAASAGGHPNSAAAAAAA 158
            |||.   .||.|..|: |.:..:.|       |..|.|    |.|. :|..:|..|......:..
Mouse    17 LAPG---CPPTGSRLRSFAINDLLGLEADLPTPAEPGLRSNSGDPA-EAIGSGPGPGPGLCGSCP 77

  Fly   159 TQMAAVNASNAFANLTGLSAAALRNVSAAQTTAVAAVASTVATIQHRLMIGNRQSLPPAG----- 218
            .:.|           ..|....|....|...:|.||..:..      |::.:.:.||.||
Mouse    78 ARGA-----------LPLGLGLLCGFGAQPPSAAAAARARC------LLLADLRLLPSAGPEPAV 125

  Fly   219 -------PPSEGSNE--------DGGFPGDGDDDSSAA------KRRRSRTNFNSWQLEELERAF 262
                   ||:.||.:        ||..|.:..:|...:      |:||.||.|.:.||||||:||
Mouse   126 AQGPVHPPPALGSQQRSESVSTSDGDSPSEEKNDPKMSLILGKRKKRRHRTVFTAHQLEELEKAF 190

  Fly   263 SASHYPDIFMREALAMRLDLKESRVAVWFQNRRAKVRKREHTKKGPGRPA----HNAQPQTCSGE 323
            ..:||||::.||.||.:.:|.|.|:.|||||||||.||||....|....|    :.|..:.|.
Mouse   191 GEAHYPDVYAREMLAAKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEYGLYGAMVRHCI-- 253

  Fly   324 PIPPNELKAKE 334
            |:|.:.|.:.:
Mouse   254 PLPDSVLNSAD 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-4	NP_573242.2	Homeodomain	244..300	CDD:459649	33/55 (60%)
Vsx1	NP_473409.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		5/10 (50%)
		Octapeptide motif	31..38		1/6 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..66		6/24 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	122..166		8/43 (19%)
		Nuclear localization signal. /evidence=ECO:0000255	168..173		1/4 (25%)
		Homeodomain	172..228	CDD:459649	33/55 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..363