DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unc-4 and Prrx2

DIOPT Version :9

Sequence 1:	NP_001285389.1	Gene:	unc-4 / 32757	FlyBaseID:	FBgn0024184	Length:	588	Species:	Drosophila melanogaster
Sequence 2:	NP_001099209.1	Gene:	Prrx2 / 113931	RGDID:	1311471	Length:	248	Species:	Rattus norvegicus

Alignment Length:	205	Identity:	74/205 - (36%)
Similarity:	94/205 - (45%)	Gaps:	38/205 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 AAAAAAATQMAAVNASNAFANLTGLSAAALRNVSAAQTTAVAAVASTVATIQHRLMIGNRQSLPP 216
            :||||.|....|.......|  .|..|.|.:|.|.:....:..||:.          |.|.:.|.
  Rat     3 SAAAAFALDPPAPGPGPPPA--PGDCAQARKNFSVSHLLDLEEVAAA----------GRRAAGPV 55

  Fly   217 AGP---------PSEGSN------EDG--GFPGDGDDDSSAAKRRRSRTNFNSWQLEELERAFSA 264
            .||         ||.||:      :||  ..||.|.......|:||:||.|||.||:.|||.|..
  Rat    56 PGPEAREGAAREPSGGSSGSEAAPQDGECAAPGHGSATKRKKKQRRNRTTFNSSQLQALERVFER 120

  Fly   265 SHYPDIFMREALAMRLDLKESRVAVWFQNRRAKVRKREHTK---------KGPGRPAHNAQPQTC 320
            :||||.|:||.||.|::|.|:||.|||||||||.|:.|...         |..|:.|...||...
  Rat   121 THYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLATRSASLLKSYGQEAAIEQPVAP 185

  Fly   321 SGEPIPPNEL 330
            ....:.|:.|
  Rat   186 RPTTLSPDYL 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unc-4	NP_001285389.1	Homeobox	246..299	CDD:278475	34/52 (65%)
unc-4	NP_001285389.1	NK	<327..>368	CDD:302627	2/4 (50%)
Prrx2	NP_001099209.1	Homeobox	104..156	CDD:395001	33/51 (65%)
		COG5576	<110..214	CDD:227863	38/86 (44%)
		OAR	222..238	CDD:397759
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000