Protein Alignment unc-4 and nobox

DIOPT Version :10

• Sequence 1: NP_573242.2
• Gene: unc-4 / 32757
• FlyBaseID: FBgn0024184
• Length: 588
• Species: Drosophila melanogaster
• Sequence 2: XP_031761569.1
• Gene: nobox / 100494031
• XenbaseID: XB-GENE-22068768
• Length: 652
• Species: Xenopus tropicalis
• Alignment Length: 487
• Identity: 116/487 - (23%)
• Similarity: 155/487 - (31%)
• Gaps: 160/487 - (32%)

  Fly     4 ETSEGDTKKFLTNNNNSSASRNNNSHNNNNNNHSPKEIPEETG-RSSSTSSNSIP----NAHRTN 63
            ||.....:|::.|       |............||.|  |||. |.....:...|    .|...|
 Frog    75 ETGPAQAEKWIRN-------RRQREDEKRCQLGSPDE--EETSLRCLEPEAGGGPQDEYRAVLIN 130

  Fly    64 AGQHLL--------GGSPSSACSTSVSGCGMPSE---GLHPTAALQLYAAAAQLAPNGVRVPPWG 117
            .|.:.|        |.:||..|::....|.:...   |..|.|....|:|.:...|.|
 Frog   131 EGGNGLVASDPREFGINPSGGCASEGGQCQLSLLAVCGPLPEATGGCYSAFSGDDPQG------- 188

  Fly   118 PFLQFGVPGVFGPNGPFLGRPRFDAASAGGHPNSAAAAAAATQMAAVNASNAFANLTGLSAAALR 182
                   ||.|.|.|.|  :| .:....|..|.||.....:.:.||......|...||..
 Frog   189 -------PGYFPPRGQF--QP-VNLKVEGNFPQSAPLPRRSARCAASCRLPTFIYDTGHG----- 238

  Fly   183 NVSAAQTTAVAAVASTVATIQHRLMIGNRQSLPPAGPPSEGSNEDGGFPGDGDDDSSAAKRRRSR 247
                                      |:||.              |..|.|..::.....|::||
 Frog   239 --------------------------GDRQR--------------GKCPADAPEEPGPPCRKKSR 263

  Fly   248 TNFNSWQLEELERAFSASHYPDIFMREALAMRLDLKESRVAVWFQNRRAKVRKREHTK-KGPGRP 311
            |.::..||:||||.|:..||||...|..:|..:.:...|:.|||||||||.||.|.|. |||.:|
 Frog   264 TLYSMDQLQELERLFAEDHYPDSEKRREIAEIIGVTPQRIMVWFQNRRAKWRKVEKTSIKGPRKP 328

  Fly   312 AHNAQPQTCSGEPIPPNELKAKERARRRKKLAKAIDRQARKLQAKGI----TVDLEALKAEYISQ 372
                                                     |.|.|:    |..|....:..:|:
 Frog   329 -----------------------------------------LSAAGMSRPETAVLTVSSSVALSR 352

  Fly   373 HKANGTFSDSDLEDDGIQIDVVGGTDSDDEGDSDAVSPVRLGGGGGGGGGTGGGGGGGASSSLHC 437
            .:|             :.:.|..|..:    ...|..||         ||...|......|:|..
 Frog   353 PEA-------------VSLSVTSGFHT----YGSAFPPV---------GGVRNGFSMVPGSALPT 391

  Fly   438 GLDGDGDSSRAGSFIGGGGSLGSPSSVA-PPS 468
            ....||.|..:.|.......|||||.|. |||
 Frog   392 SQSSDGSSQHSASCSSSSSGLGSPSEVCLPPS 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-4	NP_573242.2	Homeodomain	244..300	CDD:459649	26/55 (47%)
nobox	XP_031761569.1	Homeodomain	260..316	CDD:459649	26/55 (47%)