Protein Alignment raskol and Rasa2

DIOPT Version :9

• Sequence 1: NP_001285388.1
• Gene: raskol / 32754
• FlyBaseID: FBgn0261570
• Length: 2016
• Species: Drosophila melanogaster
• Sequence 2: XP_006510838.1
• Gene: Rasa2 / 114713
• MGIID: 2149960
• Length: 884
• Species: Mus musculus
• Alignment Length: 579
• Identity: 132/579 - (22%)
• Similarity: 228/579 - (39%)
• Gaps: 124/579 - (21%)

  Fly   602 SKQHQTEHNATSRFTNFFSKKSNPLKRTKSVTKLERTKRGSGGLRGSRSHESLLSSHAVMSTIDL 666
            |::...|...|.::.:|:....|.|:|...:.|:...|..             |.||:...|
Mouse   124 SEEFYFEIPRTFQYLSFYVYDKNVLQRDLRIGKVAIKKED-------------LCSHSGKET--- 172

  Fly   667 SCTGAVGVAPV--HQSVLGRRHCFQVRGGPRGERYYSCGSRQERDLWIYSLRKSIAPNAEHTRRT 729
                ...:.|:  :..|.|:.| .::|                       |.:.|..|....::
Mouse   173 ----WFSLQPIDSNSEVQGKVH-LELR-----------------------LNELITENGTVCQQ- 208

  Fly   730 DNSLKMWVYEAKNLPPKKRYFCELQLDKTLYG-------RTSVKLQTDLLFWGEHFDF------- 780
               |.:.:.....||......|:.....:|.|       :|.||.:|....:.|.|.|
Mouse   209 ---LVVHIKACHGLPLINGQSCDPYATVSLVGPSRNDQKKTKVKKKTSNPQFNEVFYFEVTRSSS 270

  Fly   781 -----------PDIPEINVITVNVFREVDKKKKRDKYQ--FVGSVKIPVHDVTSRLPCEQWYPIL 832
                       .||.::.:       .:|.....:..|  |:|.:|:||:.:.|....:.|| :|
Mouse   271 YSRKSQFQVEEEDIEKLEI-------RIDLWNNENLVQDVFLGEIKVPVNVLRSDSFHQAWY-LL 327

  Fly   833 SDKAGDSLGRTSGGGGSGSKDKEQLPTLRIKCRFQSTDILPINVYGNFLTYLKENYKRVCETLEP 897
            ..:          ..|:.|...:.|.:|.:...:....:||...||...|.|.::     ..::|
Mouse   328 QPR----------DNGNKSSKTDDLGSLLLTLCYTEDCVLPSEYYGPLKTLLLKS-----PDVQP 377

  Fly   898 VIGVKA----------KEDIGQALVLLMHAQGLAGAFLTDVVALDLLRVGDQRLTFRGNSLATKS 952
            |....|          |:.:...:.||:|...|. .|:|.|..|||....|....||||||||:.
Mouse   378 VSASAAYILGEICQDQKDAVLPLVRLLLHHNKLV-PFITAVAELDLKDTPDANAIFRGNSLATQC 441

  Fly   953 MEAFLKLTGEQYLQDTLSAPINELIQSERDCEVDPTKTSGSSAGSLQRQQAALRGAVRGAWQCIF 1017
            :...:|:.|..||:.||...::|:.:|.:.||:||.|.  ....:::..:..|...|...:..|.
Mouse   442 LTEMMKIVGGHYLKVTLKPVLDEICESSKSCEIDPVKL--KEGDNVENNKENLYYYVDKVFNTIV 504

  Fly  1018 ESHKHFPAQLRNCFATFRERLQQL--GRQDMADNLISASIFLRFLCPAILSPSLFNITSELPSAR 1080
            .|....|..:.:.|.:.|:...:.  ....:..:.:|:.:||||...|||||..|::....|..:
Mouse   505 GSSVSCPTVMCDIFYSLRQMAAKKFPNHPHVQYSAVSSFVFLRFFAVAILSPHAFHLRPHYPDTQ 569

  Fly  1081 ATRNLTLVAKTLQTLANF-------TRFQGKENFMEFLNDFLEQE-AARMQQFLEIIST 1131
            ..|.|||::||:|.:.|:       :||: |....|||..|.|:. ...:::||:.||:
Mouse   570 TVRTLTLISKTIQIIGNWGCQSRKKSRFK-KSVMCEFLKMFQEERYFTDVKKFLDEISS 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
raskol	NP_001285388.1	PH_RasSynGAP-like	615..729	CDD:270082	18/115 (16%)
		PH	<656..720	CDD:278594	9/65 (14%)
		C2_SynGAP_like	721..874	CDD:175980	32/179 (18%)
		RasGAP	856..1185	CDD:214617	83/296 (28%)
		RasGAP_DAB2IP	865..1192	CDD:213338	81/287 (28%)
Rasa2	XP_006510838.1	C2A_RasA2_RasA3	82..195	CDD:176046	18/114 (16%)
		C2B_RasA3	208..350	CDD:175977	30/163 (18%)
		RasGAP	359..629	CDD:383031	79/278 (28%)
		PH_GAP1m_mammal-like	626..758	CDD:241521	1/2 (50%)
		BTK	743..778	CDD:128417

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834584
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840