Protein Alignment CG8173 and PBK

DIOPT Version :9

• Sequence 1: NP_573239.1
• Gene: CG8173 / 32753
• FlyBaseID: FBgn0030864
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: NP_001265874.1
• Gene: PBK / 55872
• HGNCID: 18282
• Length: 333
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 136/402 - (33%)
• Similarity: 200/402 - (49%)
• Gaps: 95/402 - (23%)

  Fly    13 LENVQNSSTP----------------INVPPSPMMKTLGHGTGIRVYRLDRSPRLGEIRSPWAVK 61
            :|.:.|..||                ||:|.||.|:.||.|||:.||.:.|||| |...||||||
Human     1 MEGISNFKTPSKLSEKKKSVLCSTPTINIPASPFMQKLGFGTGVNVYLMKRSPR-GLSHSPWAVK 64

  Fly    62 RITQNMRVKKDTLFNERIVHEADILRKLKHPNIVGFRGVITNDEGINTLALEM-CTTSLGSILEE 125
            :|.........:::.:|::.||.||:.|.||||||:|.....::|...||:|. ...||..::||
Human    65 KINPICNDHYRSVYQKRLMDEAKILKSLHHPNIVGYRAFTEANDGSLCLAMEYGGEKSLNDLIEE 129

  Fly   126 RHDEDLGPLPAKHTYKMIMDVAQALDFLHNEAHLMHGDLKSFNVLVKGEFEICKLCDFGVSLPLD 190
            |:.....|.||....|:.:::|:.|.:||.|..|:|||:||.||::||:||..|:||.|||||||
Human   130 RYKASQDPFPAAIILKVALNMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLD 194

  Fly   191 EQ----GEVNFL----KNPGLRYVGTNLWCAPEVIDEVDVIDSKADIFSFGLVIYETLALVPPHT 247
            |.    ..:..|    .:|...|:||..|...|.::|..||..|||||:|||.::|.:.|..||
Human   195 ENMTAPAFITILLVSVTDPEACYIGTEPWKPKEAVEENGVITDKADIFAFGLTLWEMMTLSIPH- 258

  Fly   248 LELDAALGEDMDSSHDLPTDTDKLQCKQLDFSSDENKNGLPSAMEEHTDNDMSQDYDEEDDEEEK 312
                                        ::.|:|                         ||:|:|
Human   259 ----------------------------INLSND-------------------------DDDEDK 270

  Fly   313 EEEEEDDEEDDDTKENDISYFTLNNLHSAYGTRPPLPVAFQLSDDYNCVVELFYLCTNALSEDRP 377
            ..:|.|.:::        :|:      :|.|||||:.:. :|.:.|..|:|||.:|||...:|||
Human   271 TFDESDFDDE--------AYY------AALGTRPPINME-ELDESYQKVIELFSVCTNEDPKDRP 320

  Fly   378 AAKTIWQCLENN 389
            :|..|.:.||.:
Human   321 SAAHIVEALETD 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8173	NP_573239.1	PKc_like	28..389	CDD:304357	129/369 (35%)
		S_TKc	30..>245	CDD:214567	94/223 (42%)
PBK	NP_001265874.1	PKc_TOPK	32..332	CDD:270903	129/369 (35%)
		Pkinase	34..327	CDD:278497	125/362 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160438
Domainoid	1	1.000	177	1.000	Domainoid score	I3614
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32415
Inparanoid	1	1.050	213	1.000	Inparanoid score	I3648
Isobase	1	0.950	-	0	Normalized mean entropy	S3817
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1093418at2759
OrthoFinder	1	1.000	-	-		FOG0007348
OrthoInspector	1	1.000	-	-		oto90716
orthoMCL	1	0.900	-	-		OOG6_110471
Panther	1	1.100	-	-	LDO	PTHR43289
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5709
SonicParanoid	1	1.000	-	-		X5468
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.740