DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8173 and TNNI3K

DIOPT Version :9

Sequence 1:NP_573239.1 Gene:CG8173 / 32753 FlyBaseID:FBgn0030864 Length:398 Species:Drosophila melanogaster
Sequence 2:NP_057062.1 Gene:TNNI3K / 51086 HGNCID:19661 Length:835 Species:Homo sapiens


Alignment Length:241 Identity:75/241 - (31%)
Similarity:107/241 - (44%) Gaps:34/241 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 LGHGTGIRVYRLDRSPRLGEIRSP-WAVKRITQNMRVKKDTLFNERIVHEADILRKLKHPNIVGF 97
            :|.|:..:||:       |..|:. .|:||...|....|..:  :....|..||.:|.||.::.|
Human   469 IGSGSFGKVYK-------GRCRNKIVAIKRYRANTYCSKSDV--DMFCREVSILCQLNHPCVIQF 524

  Fly    98 RGVITNDEGINTLALEMCTTSLGSILEERHDE----DLGPLPAKHTYKMI--MDVAQALDFLHNE 156
            .|...||.  :..|:.....|.||:....|::    ||       ..|:|  :|||:.:::|||.
Human   525 VGACLNDP--SQFAIVTQYISGGSLFSLLHEQKRILDL-------QSKLIIAVDVAKGMEYLHNL 580

  Fly   157 AH-LMHGDLKSFNVLVKGEFEICKLCDFGVSLPLDEQGEVNFLKNPGLRYVGTNL-WCAPEVIDE 219
            .. ::|.||.|.|:|:. |.....:.|||.|..|....|.|..|.||      || |.||||..:
Human   581 TQPIIHRDLNSHNILLY-EDGHAVVADFGESRFLQSLDEDNMTKQPG------NLRWMAPEVFTQ 638

  Fly   220 VDVIDSKADIFSFGLVIYETLALVPPHTLELDAALGEDMDSSHDLP 265
            ......|||:||:.|.::|.|....|......||...||...|..|
Human   639 CTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRP 684

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8173NP_573239.1 PKc_like 28..389 CDD:304357 75/241 (31%)
S_TKc 30..>245 CDD:214567 68/219 (31%)
TNNI3KNP_057062.1 ANK <56..121 CDD:238125
ANK repeat 66..98 CDD:293786
ANK 1 66..96
ANK 99..220 CDD:238125
ANK repeat 100..131 CDD:293786
ANK 2 100..129
ANK 3 133..162
ANK repeat 134..164 CDD:293786
ANK 161..290 CDD:238125
ANK repeat 166..197 CDD:293786
ANK 4 166..195
ANK repeat 199..232 CDD:293786
ANK 5 199..228
ANK 229..360 CDD:238125
ANK 6 234..263
ANK repeat 234..262 CDD:293786
ANK repeat 269..302 CDD:293786
ANK 7 269..298
ANK repeat 304..337 CDD:293786
ANK 8 304..335
ANK 334..>401 CDD:238125
ANK repeat 339..369 CDD:293786
ANK 9 339..368
ANK 10 381..410
PKc_TNNI3K 469..722 CDD:270966 75/241 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 732..751
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0192
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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