DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8173 and pbk

DIOPT Version :9

Sequence 1:	NP_573239.1	Gene:	CG8173 / 32753	FlyBaseID:	FBgn0030864	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	XP_031757536.1	Gene:	pbk / 496810	XenbaseID:	XB-GENE-1017083	Length:	371	Species:	Xenopus tropicalis

Alignment Length:	367	Identity:	135/367 - (36%)
Similarity:	195/367 - (53%)	Gaps:	75/367 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 PINVPPSPMMKTLGHGTGIRVYRLDRSPRLGEIRSPWAVKRITQNMRVKKDTLFNERIVHEADIL 86
            |..:|.||.|:..|:|||:.||.:.|||| |..|||||:|:|::........|:.:|:..||.:|
Frog    73 PFVIPASPFMQKFGYGTGVSVYLMKRSPR-GASRSPWAIKKISKQCDASSRNLYEQRLNEEAKVL 136

  Fly    87 RKLKHPNIVGFRGVITNDEGINTLALEM-CTTSLGSILEERHDEDLGPLPAKHTYKMIMDVAQAL 150
            |.|:||||||:|....:.:|...||:|. ...||..::|||:|.:|||.||....|:..::|:.|
Frog   137 RNLQHPNIVGYRAFTKSKDGSLCLAMEYGGEKSLNDLIEERNDNELGPFPATDILKVAENMARGL 201

  Fly   151 DFLHNEAHLMHGDLKSFNVLVKGEFEICKLCDFGVSLPLDEQGEVNFLKNPGLRYVGTNLWCAPE 215
            .:||||..::|||:||.||:|||:||..|:||.||||||||.   ..:.:|...|:||..|...|
Frog   202 KYLHNEKRILHGDIKSSNVVVKGDFESVKICDVGVSLPLDEN---MIVSDPKAYYIGTESWKPKE 263

  Fly   216 VIDEVDVIDSKADIFSFGLVIYETLALVPPHTLELDAALGEDMDSSHDLPTDTDKLQCKQLDFSS 280
            .:||..||..|:||::|||.::|.::|..||.               :||
Frog   264 ALDEGGVITDKSDIYAFGLTLWEMMSLSIPHL---------------NLP--------------- 298

  Fly   281 DENKNGLPSAMEEHTDNDMSQDYDEEDDEEEKEEEEEDDEEDDDTKENDISYFTLNNLHSAYGTR 345
                                    .|||||:..:|::.||:         :|:      .|.|||
Frog   299 ------------------------PEDDEEDTFDEDDFDED---------AYY------EALGTR 324

  Fly   346 PPLPVAFQLSDDYNCVVELFYLCTNALSEDRPAAKTIWQCLE 387
            |||.:. :|.|.|..|:||||:|.:...:.||:|..|.:.||
Frog   325 PPLNME-ELDDSYQKVIELFYMCAHEDPKLRPSAAKIIEVLE 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8173	NP_573239.1	PKc_like	28..389	CDD:304357	133/361 (37%)
CG8173	NP_573239.1	S_TKc	30..>245	CDD:214567	96/215 (45%)
pbk	XP_031757536.1	PKc_TOPK	79..367	CDD:270903	133/361 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	194	1.000	Domainoid score	I3122
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32415
Inparanoid	1	1.050	223	1.000	Inparanoid score	I3435
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1093418at2759
OrthoFinder	1	1.000	-	-		FOG0007348
OrthoInspector	1	1.000	-	-		oto104509
Panther	1	1.100	-	-	LDO	PTHR43289
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5468
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.070