DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8173 and slpr

DIOPT Version :9

Sequence 1:	NP_573239.1	Gene:	CG8173 / 32753	FlyBaseID:	FBgn0030864	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_001188558.1	Gene:	slpr / 44111	FlyBaseID:	FBgn0030018	Length:	1155	Species:	Drosophila melanogaster

Alignment Length:	314	Identity:	72/314 - (22%)
Similarity:	115/314 - (36%)	Gaps:	87/314 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 QNMRVKKDTLFNERIVHEADILRKLKHPNIVGFRGVITNDEGINTLALEMCTT-------SLGSI 122
            |.||        :.::.||.:...|||.||...|||..|        .::|..       ||..|
  Fly   167 QRMR--------DNVLQEAKLFWALKHENIAALRGVCLN--------TKLCLVMEYARGGSLNRI 215

  Fly   123 LEERHDEDLGPLPAKHTYKMIMDVAQALDFLHNEA--HLMHGDLKSFNVLVKGEFE-------IC 178
            |       .|.:|........:.:|:.:::|||||  .::|.||||.|||:....|       ..
  Fly   216 L-------AGKIPPDVLVNWAIQIARGMNYLHNEAPMSIIHRDLKSSNVLIYEAIEGNHLQQKTL 273

  Fly   179 KLCDFGVSLPLDEQGEVNFLKNPGLRYVGTNLWCAPEVIDEVDVIDSKADIFSFGLVIYE----- 238
            |:.|||::..:        .....:...||..|..|||| .|......:|::|:|::::|
  Fly   274 KITDFGLAREM--------YNTQRMSAAGTYAWMPPEVI-SVSTYSKFSDVWSYGVLLWELITGE 329

  Fly   239 ------------------TLALVPPHTL-ELDAALGED--MDSSHDLP------TDTDKLQCKQL 276
                              ||.|..|.|. |...||.:.  ....|..|      ...:.:.|.:.
  Fly   330 TPYKGFDPLSVAYGVAVNTLTLPIPKTCPETWGALMKSCWQTDPHKRPGFKEILKQLESIACSKF 394

  Fly   277 DFSSDENKNGLPSAMEEHTDNDMSQDYDEEDDEEEKEEEEEDDEEDDDTKENDI 330
            ..:..|:.:.:.....:.....:       .|..|||:..:..||:...||..:
  Fly   395 TLTPQESFHYMQECWRKEIAGVL-------HDLREKEKRFQTIEEELRNKEEQL 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8173	NP_573239.1	PKc_like	28..389	CDD:304357	72/314 (23%)
CG8173	NP_573239.1	S_TKc	30..>245	CDD:214567	55/218 (25%)
slpr	NP_001188558.1	SH3_MLK	47..104	CDD:212809
		TyrKc	129..386	CDD:197581	62/250 (25%)
		STKc_MLK	134..389	CDD:270963	62/253 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810