DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8173 and ANKK1

DIOPT Version :9

Sequence 1:	NP_573239.1	Gene:	CG8173 / 32753	FlyBaseID:	FBgn0030864	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	XP_011541038.1	Gene:	ANKK1 / 255239	HGNCID:	21027	Length:	776	Species:	Homo sapiens

Alignment Length:	186	Identity:	50/186 - (26%)
Similarity:	94/186 - (50%)	Gaps:	26/186 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 IVHEADILRKLKHPNIVGFRGVITNDEGINTLALEMCTTSLGSILEERHDEDLGPLPAKHT---- 139
            ::.||..::|:|..:||...||              |...||.::|...:..|..:.:.|:
Human    68 LIEEAAKMKKIKFQHIVSIYGV--------------CKQPLGIVMEFMANGSLEKVLSTHSLCWK 118

  Fly   140 --YKMIMDVAQALDFLHN-EAHLMHGDLKSFNVLVKGEFEICKLCDFGVSLPLDEQGEVNFLKNP 201
              :::|.:.:.|::|||: :..|:|.|||..|:|:.....: |:.|||:|..:::...:.:::..
Human   119 LRFRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHV-KISDFGLSKWMEQSTRMQYIERS 182

  Fly   202 GLRYVGTNLWCAPEVIDEVDVIDS-KADIFSFGLVIYETLALVPPHTLELDAALGE 256
            .||  |...:..||:..|.:.... |.|::||.:||:|.|....|:: ||.:.|.|
Human   183 ALR--GMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKKPYS-ELTSQLKE 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8173	NP_573239.1	PKc_like	28..389	CDD:304357	50/186 (27%)
CG8173	NP_573239.1	S_TKc	30..>245	CDD:214567	45/173 (26%)
ANKK1	XP_011541038.1	STKc_RIP4_like	25..303	CDD:270927	50/186 (27%)
		S_TKc	26..291	CDD:214567	50/186 (27%)
		ANK repeat	375..403	CDD:293786
		Ank_2	377..468	CDD:289560
		ANK	400..524	CDD:238125
		ANK repeat	405..436	CDD:293786
		ANK repeat	438..469	CDD:293786
		Ank_2	443..534	CDD:289560
		ANK repeat	471..502	CDD:293786
		ANK	499..623	CDD:238125
		ANK repeat	504..534	CDD:293786
		ANK repeat	537..568	CDD:293786
		Ank_4	539..591	CDD:290365
		ANK	565..690	CDD:238125
		ANK repeat	570..601	CDD:293786
		Ank_2	575..665	CDD:289560
		ANK repeat	603..634	CDD:293786
		ANK	638..755	CDD:238125
		ANK repeat	638..667	CDD:293786
		Ank_2	641..733	CDD:289560
		ANK repeat	669..700	CDD:293786
		ANK repeat	702..733	CDD:293786
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0192
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900