DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8173 and Ripk2

DIOPT Version :9

Sequence 1:NP_573239.1 Gene:CG8173 / 32753 FlyBaseID:FBgn0030864 Length:398 Species:Drosophila melanogaster
Sequence 2:NP_620402.1 Gene:Ripk2 / 192656 MGIID:1891456 Length:539 Species:Mus musculus


Alignment Length:267 Identity:67/267 - (25%)
Similarity:124/267 - (46%) Gaps:42/267 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    25 VPPSPMMKTLGHGTGIRVYRLDRSPRLGEIRS----PWAVKRITQNMRVKKDTLFNER--IVHEA 83
            :||.|..|...      ::.|.|... |.:.|    .|.|:...:::.:....|.:||  |:.||
Mouse    10 LPPIPYHKLAD------LHYLSRGAS-GTVSSARHADWRVRVAVKHLHIHTPLLDSERNDILREA 67

  Fly    84 DILRKLKHPNIVGFRGVITNDEGINTLALEMCTTSLGSILEERHD-EDLG-PLPAKHTYKMIMDV 146
            :||.|.:...|:...|:....|.:..:...|...||..:|..:.: .|:. ||    .::::.::
Mouse    68 EILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDIAWPL----RFRILHEI 128

  Fly   147 AQALDFLHN-EAHLMHGDLKSFNVLVKGEFEICKLCDFGVS----LPLDEQGEVNFLKNP-GLRY 205
            |..:::||| ...|:|.|||:.|:|:..||.: |:.|||:|    :.|.:..  ::...| |   
Mouse   129 ALGVNYLHNMNPPLLHHDLKTQNILLDNEFHV-KIADFGLSKWRMMSLSQSR--SYKSAPEG--- 187

  Fly   206 VGTNLWCAPEVID--EVDVIDSKADIFSFGLVIYETLA-------LVPPHTLELDAALGEDMDSS 261
             ||.::..||..:  :......|.||:|:.::::|.|:       :..|..:....:.|...|:|
Mouse   188 -GTIIYMPPENYEPGQKSRASVKHDIYSYAVIMWEVLSRKQPFEEVTNPLQIMYSVSQGHRPDTS 251

  Fly   262 HD-LPTD 267
            .: ||.|
Mouse   252 EENLPFD 258

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8173NP_573239.1 PKc_like 28..389 CDD:304357 65/264 (25%)
S_TKc 30..>245 CDD:214567 57/237 (24%)
Ripk2NP_620402.1 STKc_RIP2 20..303 CDD:270928 63/257 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 335..368
CARD_RIP2_CARD3 437..522 CDD:176764
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 519..539
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0192
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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