Protein Alignment par-6 and pard6a

DIOPT Version :9

• Sequence 1: NP_573238.1
• Gene: par-6 / 32752
• FlyBaseID: FBgn0026192
• Length: 351
• Species: Drosophila melanogaster
• Sequence 2: NP_001093521.2
• Gene: pard6a / 792828
• ZFINID: ZDB-GENE-070705-215
• Length: 385
• Species: Danio rerio
• Alignment Length: 392
• Identity: 177/392 - (45%)
• Similarity: 237/392 - (60%)
• Gaps: 57/392 - (14%)

  Fly     1 MSKNKINTTSATAASDTNLIEVKSKFDAEFRRWSFKRNEAEQSFDKFASLIEQLHKLTNIQFLIL 65
            ||:|.    ..|..::.:::||||||:.|:||::.|:|..  .|.:|..|::.:|::..:..|:.
Zfish     1 MSRNH----RTTLKNEESVVEVKSKFEGEYRRFALKKNTG--GFQEFYQLLQTIHRIPGVDVLLG 59

  Fly    66 YIDPRDNDLLPINNDDNFGRALKTARPLLRVIVQRK--DDLNEYSGFGTMKPRNLIGSILMGHTP 128
            |.|.. .||||||||.||.:||.:|.||||:|||::  ||...:. .|:::.|......|....|
Zfish    60 YADIH-GDLLPINNDYNFHKALSSANPLLRIIVQKRVVDDTVPFP-TGSLQRRKKGPGGLRQAQP 122

  Fly   129 VKTKAPSISIPHDFRQVSAIIDVDIVPETHRRVRLLKHGSDKPLGFYIRDGTSVRVTASGLEKQP 193
             |::.|.|.:|.||||:|:||||||:||||.||||.|||:.||||||||||.|||||:.|:||.|
Zfish   123 -KSRPPLIGLPQDFRQISSIIDVDILPETHLRVRLHKHGTHKPLGFYIRDGVSVRVTSHGVEKFP 186

  Fly   194 GIFISRLVPGGLAESTGLLAVNDEVIEVNGIEVAGKTLDQVTDMMVANSSNLIITVKPANQRTLT 258
            ||||||||.||||::||||.||||::|||||:|:||:||||||||||||.|||:|||||..|:|.
Zfish   187 GIFISRLVKGGLADTTGLLGVNDEILEVNGIDVSGKSLDQVTDMMVANSHNLIVTVKPAIYRSLD 251

  Fly   259 STHR---------GSFSRNSQLSSGSHH------TNNTNTSDEIEHDDQDDIVDLTGVTLDESPT 308
            .|:|         .:.||.|.||..|.|      |:..:.|:.:...|.||..||   .::....
Zfish   252 DTYRTFKTSAGNSSAGSRGSALSHDSAHSPASQNTSQYSNSNSVAEGDSDDDTDL---IIENDNL 313

  Fly   309 STSA--------GNHN---------HQP-------PLSSSPSS----HHQQAASNASTIMASDVK 345
            ||.|        |:|.         |:|       |.|||.||    .|..:.:..|:...|..:
Zfish   314 STYAQNRLTNGNGSHGNAQSSGAFAHRPLPQSVSLPSSSSLSSLTTPTHNGSPTKTSSSQESMRE 378

  Fly   346 DG 347
            ||
Zfish   379 DG 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
par-6	NP_573238.1	PB1_Par6	20..101	CDD:99724	38/80 (48%)
		PDZ_signaling	159..250	CDD:238492	70/90 (78%)
pard6a	NP_001093521.2	PB1_Par6	16..94	CDD:99724	38/80 (48%)
		PDZ_signaling	153..243	CDD:238492	70/89 (79%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586325
Domainoid	1	1.000	138	1.000	Domainoid score	I4832
eggNOG	1	0.900	-	-		E1_KOG3606
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I2768
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D356104at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24683
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14102
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1143
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.860