DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment par-6 and C09G1.4

DIOPT Version :9

Sequence 1:	NP_573238.1	Gene:	par-6 / 32752	FlyBaseID:	FBgn0026192	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	NP_510621.2	Gene:	C09G1.4 / 181679	WormBaseID:	WBGene00007486	Length:	545	Species:	Caenorhabditis elegans

Alignment Length:	222	Identity:	62/222 - (27%)
Similarity:	96/222 - (43%)	Gaps:	52/222 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 PRDNDLLPINNDDNFGRALKTARPLL----RVIVQRKDDLNEYSG--FGTMK---------PRNL 118
            |...|.|.|||.:...|.|.|| ||:    ::.:...|:|..|..  |..|:         |::.
Worm   331 PGSLDNLHINNLNMRRRKLPTA-PLMGSSCQLHLDNSDELTAYRALQFQMMQDELQRQQPPPQSF 394

  Fly   119 IGSILMGHT-----------PVKTKAP-----SISIPHDFRQ-------VSAIIDVDIVPETHRR 160
            ....|:..|           .:.|..|     .:|:|..:.|       |.|.: |.:.....||
Worm   395 ERPTLLRRTNMPQQQSFNIPHITTTGPPPPAMGLSVPVQYDQGEYGTQSVRAQL-VALDQRGFRR 458

  Fly   161 VRLLKHGSDKPLGFYIRDGTSVRVTASGLEKQPGIFISRLVPGGLAESTGLLAVNDEVIEVNGIE 225
            | |::.....|.||||..|    |.|.   ::.||||||:   .|...:.:|.|.||:|.|:...
Worm   459 V-LVEKMMPGPFGFYIATG----VVAG---QRAGIFISRV---SLPSLSPMLTVGDEIIYVDEEY 512

  Fly   226 VAGKTLDQVTDMMVANSSNLIITVKPA 252
            |.|::|:.| ..::|..:::.||:.||
Worm   513 VKGRSLEYV-QSVIAGKTSVTITLLPA 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
par-6	NP_573238.1	PB1_Par6	20..101	CDD:99724	12/35 (34%)
par-6	NP_573238.1	PDZ_signaling	159..250	CDD:238492	32/90 (36%)
C09G1.4	NP_510621.2	PDZ_signaling	457..536	CDD:238492	32/90 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14102
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100