DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment par-6 and si:ch211-13f8.1

DIOPT Version :9

Sequence 1:	NP_573238.1	Gene:	par-6 / 32752	FlyBaseID:	FBgn0026192	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	XP_021322446.1	Gene:	si:ch211-13f8.1 / 101882577	ZFINID:	ZDB-GENE-061207-4	Length:	1068	Species:	Danio rerio

Alignment Length:	218	Identity:	60/218 - (27%)
Similarity:	87/218 - (39%)	Gaps:	53/218 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 SFKRNEAEQSFDKFASLIEQLHKLTNIQFLILYIDPRDNDLLPINNDDNFGRALKTARPLLRVIV 98
            |.||..:.||... .|.:.||.|.:::|.|   ..|:..                         .
Zfish   895 SLKRTPSLQSLHT-ESPLAQLRKASSVQSL---QSPKRK-------------------------F 930

  Fly    99 QRKDDLNEYSGFGTMKPRNLIGSILMGHTPVKTKAPSISIPHDFRQVSAIIDVDIVPETHRRVRL 163
            :|...|.|.|...::.||:|            .|...|....|.|.....: |...|:....:.|
Zfish   931 ERSTILGELSLPLSLAPRDL------------QKEECIEALEDSRGPQGRL-VQAFPDGTLLIEL 982

  Fly   164 LKHGSDKPLGFYIRDGTSVRVTASGLEKQPGIFISRLVPGGLAES--TGLLAVNDEVIEVNGIEV 226
            ::...:||.||.|..|..        ....||::.| |..|:.|:  ||||.|.||::||||..:
Zfish   983 IRPADNKPFGFVISRGKG--------RPDSGIYVER-VGDGVTENSYTGLLGVGDEILEVNGEII 1038

  Fly   227 AGKTLDQVTDMMVANSSNLIITV 249
            ||.||||||.:|..::...|.|:
Zfish  1039 AGLTLDQVTRLMTRDTKATIRTL 1061

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
par-6	NP_573238.1	PB1_Par6	20..101	CDD:99724	12/66 (18%)
par-6	NP_573238.1	PDZ_signaling	159..250	CDD:238492	35/93 (38%)
si:ch211-13f8.1	XP_021322446.1	DUF4685	338..452	CDD:318034
si:ch211-13f8.1	XP_021322446.1	PDZ_signaling	979..1050	CDD:238492	32/79 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3606
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14102
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910