DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8188 and Ube2s

DIOPT Version :9

Sequence 1:	NP_001033852.1	Gene:	CG8188 / 32751	FlyBaseID:	FBgn0030863	Length:	209	Species:	Drosophila melanogaster
Sequence 2:	NP_598538.1	Gene:	Ube2s / 77891	MGIID:	1925141	Length:	223	Species:	Mus musculus

Alignment Length:	228	Identity:	128/228 - (56%)
Similarity:	153/228 - (67%)	Gaps:	31/228 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SNVENLSPQTIRQVMRELQEMETTPPEGIKVLINESDVTDIQALIDGPAGTPYAAGIFRVKLTLN 70
            ||||||.|..||.|.:|:..:...||:||||..||.|:||:|..|:||.|||||.|:||:||.|.
Mouse     3 SNVENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLG 67

  Fly    71 KDFPLTPPKAYFLTKIFHPNVAANGEICVNTLKKDWKPDLGIKHILLTIKCLLIVPNPESALNEE 135
            ||||.:|||.|||||||||||..|||||||.||:||..:|||:|:|||||||||.||||||||||
Mouse    68 KDFPASPPKGYFLTKIFHPNVGPNGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEE 132

  Fly   136 AGKMLLERYDDYSQRARMMTEIH-------------AQPAKCGV----------GAVGDAKDDGG 177
            ||::|||.|::|:.|||::||||             .|....|.          |.:|.|:   |
Mouse   133 AGRLLLENYEEYAARARLLTEIHGGACSTSSGRAEATQDLASGASASSADPMIPGVLGGAE---G 194

  Fly   178 PSTKKHAG-LDKKLQDKKKEKLLKEKKRMLKRL 209
            |..||||| .||||..|||    .:|||.|:||
Mouse   195 PMAKKHAGERDKKLAAKKK----LDKKRALRRL 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8188	NP_001033852.1	COG5078	12..159	CDD:227410	97/159 (61%)
CG8188	NP_001033852.1	UBCc	16..155	CDD:238117	92/138 (67%)
Ube2s	NP_598538.1	UQ_con	16..152	CDD:306648	90/135 (67%)
Ube2s	NP_598538.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	170..223		23/59 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850365
Domainoid	1	1.000	200	1.000	Domainoid score	I3028
eggNOG	1	0.900	-	-		E2759_KOG0423
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56676
Inparanoid	1	1.050	240	1.000	Inparanoid score	I3332
Isobase	1	0.950	-	0	Normalized mean entropy	S899
OMA	1	1.010	-	-		QHG53499
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007037
OrthoInspector	1	1.000	-	-		otm43029
orthoMCL	1	0.900	-	-		OOG6_103684
Panther	1	1.100	-	-	LDO	PTHR24068
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4812
SonicParanoid	1	1.000	-	-		X5130
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740