DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8188 and ube2s

DIOPT Version :9

Sequence 1:	NP_001033852.1	Gene:	CG8188 / 32751	FlyBaseID:	FBgn0030863	Length:	209	Species:	Drosophila melanogaster
Sequence 2:	NP_001020707.1	Gene:	ube2s / 565498	ZFINID:	ZDB-GENE-050913-92	Length:	221	Species:	Danio rerio

Alignment Length:	229	Identity:	117/229 - (51%)
Similarity:	146/229 - (63%)	Gaps:	35/229 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SNVENLSPQTIRQVMRELQEMETTPPEGIKVLINESDVTDIQALIDGPAGTPYAAGIFRVKLTLN 70
            ||||||.||.:|.|.:|:..:...||||||:..:|.|:|::...|:||.|||||.|:||::|.|.
Zfish     3 SNVENLPPQVLRLVYKEVSALAADPPEGIKIYPSEEDITELHTSIEGPEGTPYAGGVFRMRLVLG 67

  Fly    71 KDFPLTPPKAYFLTKIFHPNVAANGEICVNTLKKDWKPDLGIKHILLTIKCLLIVPNPESALNEE 135
            ||||..||:.|||||||||||...||||||.||:|||.:||::|:|||||||||.||||||||||
Zfish    68 KDFPAVPPRGYFLTKIFHPNVGHKGEICVNVLKRDWKAELGLRHVLLTIKCLLIHPNPESALNEE 132

  Fly   136 AGKMLLERYDDYSQRARMMTEIHAQPAKCGVGAVGDAKDD--GGPSTKKHAGLDKK--------- 189
            |||:|||.|.:|:.||.::|||||      :|....|..:  .||..|||||...|
Zfish   133 AGKLLLEDYKEYASRAHLLTEIHA------MGGTSGAPQEPADGPQPKKHAGDPNKRVVGAGLPT 191

  Fly   190 --------------LQDKKKEKLLKEKKRMLKRL 209
                          :..|||    .:|||.|:||
Zfish   192 MGTGTNNSNISNTNIVAKKK----TDKKRALRRL 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8188	NP_001033852.1	COG5078	12..159	CDD:227410	90/146 (62%)
CG8188	NP_001033852.1	UBCc	16..155	CDD:238117	85/138 (62%)
ube2s	NP_001020707.1	COG5078	10..157	CDD:227410	92/152 (61%)
		UBCc	14..152	CDD:238117	85/137 (62%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	158..221		17/66 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596285
Domainoid	1	1.000	190	1.000	Domainoid score	I3206
eggNOG	1	0.900	-	-		E2759_KOG0423
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56676
Inparanoid	1	1.050	227	1.000	Inparanoid score	I3460
OMA	1	1.010	-	-		QHG53499
OrthoDB	1	1.010	-	-		D1412570at2759
OrthoFinder	1	1.000	-	-		FOG0007037
OrthoInspector	1	1.000	-	-		oto38828
orthoMCL	1	0.900	-	-		OOG6_103684
Panther	1	1.100	-	-	LDO	PTHR24068
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4812
SonicParanoid	1	1.000	-	-		X5130
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800