DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8188 and UBE2K

DIOPT Version :9

Sequence 1:	NP_001033852.1	Gene:	CG8188 / 32751	FlyBaseID:	FBgn0030863	Length:	209	Species:	Drosophila melanogaster
Sequence 2:	NP_005330.1	Gene:	UBE2K / 3093	HGNCID:	4914	Length:	200	Species:	Homo sapiens

Alignment Length:	151	Identity:	43/151 - (28%)
Similarity:	86/151 - (56%)	Gaps:	1/151 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 NLSPQTIRQVMRELQEMETTPPEGIKVLINESDVTDIQALIDGPAGTPYAAGIFRVKLTLNKDFP 74
            |::.|.|::..:|:.:.|.|....|||.:.:.:.|:::..|.||..|||..|.:::::.:.:.:|
Human     3 NIAVQRIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPETYP 67

  Fly    75 LTPPKAYFLTKIFHPNVAA-NGEICVNTLKKDWKPDLGIKHILLTIKCLLIVPNPESALNEEAGK 138
            ..|||..|:|||:|||::: .|.||::.||..|...:.::.:||:::.||....|:...:.....
Human    68 FNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVAN 132

  Fly   139 MLLERYDDYSQRARMMTEIHA 159
            ...:..:.:.|.||:...::|
Human   133 QYKQNPEMFKQTARLWAHVYA 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8188	NP_001033852.1	COG5078	12..159	CDD:227410	41/147 (28%)
CG8188	NP_001033852.1	UBCc	16..155	CDD:238117	40/139 (29%)
UBE2K	NP_005330.1	UBCc	6..149	CDD:238117	41/142 (29%)
UBE2K	NP_005330.1	UBA_II_E2_UBE2K	163..200	CDD:270573
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910