DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12990 and CG9447

DIOPT Version :9

Sequence 1:	NP_573233.1	Gene:	CG12990 / 32747	FlyBaseID:	FBgn0030859	Length:	663	Species:	Drosophila melanogaster
Sequence 2:	NP_610243.4	Gene:	CG9447 / 35597	FlyBaseID:	FBgn0033110	Length:	656	Species:	Drosophila melanogaster

Alignment Length:	558	Identity:	116/558 - (20%)
Similarity:	214/558 - (38%)	Gaps:	139/558 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 AKKPELKTNFFDSGAVQIFFVVLGVTLLLTLAAT--------------------SGLGKYSRILA 227
            |...:||.:..|..    |:.:|.|.|.:||.::                    ..:.:..|:|.
  Fly   139 ASDKDLKMDLLDLA----FYGILVVILFITLCSSFLDYRLSKMNSQKSESFYREPLMDRRQRLLT 199

  Fly   228 CFDFADNWRLAWKPVNPSQENRPV---NGLRVLTAFSLIGVHVI------------WYK--YFSV 275
            .|....|:....:|.| |..:|.|   :|.||:..|.:|..|.:            :::  .|..
  Fly   200 SFSVVRNYHRLVEPYN-SDFSRDVSFFDGFRVIGVFVVILGHTLMVFMTVPIENPEFFEQFLFRF 263

  Fly   276 DPSVEMLGKLSSMTMRHTYWPTMVEIFFVVSGYLTVLNFIRDEQLQKDIASDGILGNMRRYLREF 340
            :.|:...|.|            :::||||:||:|..:.|.:.:|:|   ...|.|..:..|.|.|
  Fly   264 ETSIFQNGSL------------VIQIFFVMSGFLLYVKFTKRQQIQ---PKTGTLECIAVYFRVF 313

  Fly   341 IHRYCRLAPLQFVIVLM-GVVVIEYQRQVSVMQITDPQDELCRLNAVRNVFFIQNLFPIQFMCGS 404
            .:||.||.|....::|. |.:::..|.......:|:.:...||.|..:||||:.| ..::..|..
  Fly   314 SYRYFRLLPSLLALILFNGTLLVRLQNGPFWRHLTEAERVFCRANWWKNVFFVTN-HMLEDSCSH 377

  Fly   405 WTWSLGCDMQLHMTAMLLLFMHTKHPNMVKWIVRLLVVISALFSIVFMEVNEVGANFEEMYHTNE 469
            .||.||.||||....::::.:..|||.:.:.|...|:.::.....|...|.|:    :.:||...
  Fly   378 QTWYLGADMQLFELFLIVIIITKKHPKLTRTIYTTLLALAFAVPAVLTYVLEL----DGIYHIRP 438

  Fly   470 WSYMSPLIRMLAYIIGGSYAFFQVKGT-------------GTPFDLVMPNWWI--RLGAIACIGW 519
            .:|              .|.:|:...|             |..|..:..::::  |.|.:..:|.
  Fly   439 ETY--------------RYLYFRHSDTFYQMYPPFYTNLGGYLFGFLCGHFYLRQRSGNVELLGH 489

  Fly   520 LARQVTMDQLPAISIILSFMVVLRILVSTAASHLIICGTKPDNSDSYAPTRWL------------ 572
            |...:.|           :::||..|....:.::.|      ..|...|:.||
  Fly   490 LKYDLAM-----------WLLVLATLGVLFSGYIFI------RQDFAKPSLWLALYAGIHKILWV 537

  Fly   573 -----LALLQSEQV-------------QRISKFTYAIYLLNPIVIMYVYHSFSNEVYPDNTMMIM 619
                 ..:|...:|             :.:::.::..:|.:.:|:..|..:|...||..:..::.
  Fly   538 LICAGFVILMCRKVGGIAYDFCTLPAFRPLARISFQSFLWHIVVLRTVAGNFRQPVYVSSFFLLC 602

  Fly   620 LAISCSVVCYLWAIVMTVLFEIPFNRLTSVMINSRSSP 657
            ...|..::....|.::.||.|.||..:...:|.....|
  Fly   603 NVFSVFILTQFVAALVAVLLEYPFVEVLRCLIKPEKGP 640

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12990	NP_573233.1	NRF	61..162	CDD:214781
		Acyl_transf_3	251..637	CDD:280013	91/448 (20%)
		OafA	295..660	CDD:224748	87/409 (21%)
CG9447	NP_610243.4	Acyl_transf_3	222..611	CDD:280013	90/439 (21%)
CG9447	NP_610243.4	OafA	225..631	CDD:224748	95/456 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453339
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940