DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12990 and oac-7

DIOPT Version :9

Sequence 1:	NP_573233.1	Gene:	CG12990 / 32747	FlyBaseID:	FBgn0030859	Length:	663	Species:	Drosophila melanogaster
Sequence 2:	NP_507120.3	Gene:	oac-7 / 180096	WormBaseID:	WBGene00007835	Length:	702	Species:	Caenorhabditis elegans

Alignment Length:	737	Identity:	133/737 - (18%)
Similarity:	254/737 - (34%)	Gaps:	252/737 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 KCEEQLLELRRAWQDHQSWALKAIDASGEGYANFMMGQRAWLGNRFTCRAVNE-PMLQDMTIKN- 105
            ||.::.:::.:    ...:|::.:||.|                :.....:.| |::.|.:.:.
Worm    71 KCNKKEIQIIK----DNFYAIEQLDAFG----------------KLPSSGIFEVPLIFDGSYQEC 115

  Fly   106 QRLLREMSPIQFHYLVAYIESNSPWQL---EVTIKANPLLHIGLCLPASCDVPEVEQLIRK---- 163
            ||:..:.....:.|||.....||...:   ...:.:........|:..||...::.||..:
Worm   116 QRISGKKYETNYCYLVLVPGRNSSCSIGGGGGFLPSAAFFRSATCMSVSCTSEDLPQLFNQLPLM 180

  Fly   164 ------------SMAKEESFHCWDMDAKLAYAKKPELKTNFFDSGAVQIFFVVLGVTLLLTLAAT 216
                        .:.|:.:|  |...|.:.                     |::.:.:|.|
Worm   181 PFTACAAFCSSFPVEKDSAF--WGFSAFMC---------------------VMISILVLAT---- 218

  Fly   217 SGLGKYSRILACFDFADNWRLAWK-----PVNPS---------------------QENRP----- 250
                          |.|..:.|.|     |..|:                     :|.:|
Worm   219 --------------FIDYLKDAMKNEHSPPPQPNLIMKMLLTFSLWTNAGVLLSVKEQKPGFIKC 269

  Fly   251 VNGLRVLTAFSLIGVHVIWYKYFSVDPSVEMLGKLSSMTMRH---TYWPTM-------VEIFFVV 305
            ::.:|.|:...::..|..   .|.:.|.       :.::|.|   .:|..:       |:.||::
Worm   270 LDCIRFLSMLWVVTGHTF---TFVIPPD-------TLLSMSHFTDHFWNHLLLNAFVSVDTFFLL 324

  Fly   306 SGYLTVLNFIRDEQLQKDIASDGILGNMRRYLREFIHRYCRLAPLQFVIVLMGVVVIEY-QRQVS 369
            ||.:....|.:.:.....|.|.      ..::..::|||.||.|...:.:...:|..:| |...|
Worm   325 SGIVVAYLFFKQKHKSSQIKSP------LTWIIFYMHRYLRLTPPYMIFIGFYIVYGKYVQGPFS 383

  Fly   370 VMQITDPQDEL--CRLNAVRNVFFIQNLFPIQFMCGSWTWSLGCDMQLHMTAMLLL----FMHTK 428
            ..|.......:  |.....:|:|:|.|:......|.:.:|.|..|.||::.|.::|    :....
Worm   384 ASQFNTLLSSIATCESYWWKNLFYINNMGDSSTACYAPSWYLAVDTQLYIFAPIILVGLYYSAII 448

  Fly   429 HPNMVK-WIVRLLVVISALFSIVFMEVNEVGANFEEMYHTN---EWSYMSPLIRMLAYIIG---- 485
            ..:::. .::..||.:..|:||.     ::.|:|....:||   :..|..|.||...|:||
Worm   449 GSSLIAVGMIGSLVTVYILYSIY-----DLPADFFGNGNTNLLYDMIYHKPWIRCPPYLIGLLIG 508

  Fly   486 -GSYAFFQVKGTGTPFDLVMPNWWIRLGAIACIGWL---------------------------AR 522
             |...|.|.|        :..:|:     :|.||||                           |.
Worm   509 YGLAVFGQRK--------IRIHWF-----LAVIGWLVAFGLGMACMFSTYDYDKGAYWSIFARAT 560

  Fly   523 QVTMDQLPAISIILSFMVVLRILVSTAASHLIICGTKPDNSDSYAPTRW---LLALLQSEQVQRI 584
            .....:: |.||.:|:::|        |:|:                .|   :.|.:.....|.:
Worm   561 YYNFSRI-AWSIAVSWVIV--------ANHM----------------GWGGPIDAFMSHPMWQPL 600

  Fly   585 SKFTYAIYLLNPIVI----------MYVYHSFSNEVYPDNTMMIMLAISCSVVCYLWAIVMTVLF 639
            .:.:|..|:::...:          |:.|.:|.        :.|..|:...::.|::|...:.||
Worm   601 GRLSYCAYIVHFFTLFWYLNINDSSMHFYSTFQ--------VFIYYAVPACLLSYIFAFFWSSLF 657

  Fly   640 EIPFNRLTSVMI------NSRS 655
            |||..:|..:||      |.||
Worm   658 EIPILKLKKMMIEAILQRNQRS 679

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12990	NP_573233.1	NRF	61..162	CDD:214781	19/105 (18%)
		Acyl_transf_3	251..637	CDD:280013	86/451 (19%)
		OafA	295..660	CDD:224748	90/430 (21%)
oac-7	NP_507120.3	NRF	83..191	CDD:214781	19/123 (15%)
oac-7	NP_507120.3	OafA	261..666	CDD:224748	94/471 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161223
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850