DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12990 and oac-39

DIOPT Version :9

Sequence 1:	NP_573233.1	Gene:	CG12990 / 32747	FlyBaseID:	FBgn0030859	Length:	663	Species:	Drosophila melanogaster
Sequence 2:	NP_001300160.1	Gene:	oac-39 / 178553	WormBaseID:	WBGene00006419	Length:	739	Species:	Caenorhabditis elegans

Alignment Length:	797	Identity:	160/797 - (20%)
Similarity:	293/797 - (36%)	Gaps:	225/797 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LLVLLLLQIIAALG-------DVDNCEPKSLAKDLI----EMVPQREN----------------- 38
            ::.||:|.::.:||       :.|..:..:|..:|:    |::.|.|.
Worm     1 MVELLVLFVVISLGIVPSNGLEFDPNKAMALLGELMAHPREVMEQLEKYKTSDLIAALGIHSFSK 65

  Fly    39 -TTLSKCEEQLLELRRAWQD------HQSWA--------------LKAIDASGEGYANFMMGQRA 82
             |...:|.|:|..|.....|      ||:.|              :..:||:|:..:....|...
Worm    66 YTISEECHEELAFLGYGMIDVARHVKHQTTAAPSTMTDVEKTRYLIPMMDAAGKIGSGIARGHIL 130

  Fly    83 WLGNRFTCRAVNEPMLQDMTIKNQRLLREMSPIQFHYLVAYIESNSPWQLEVTIKANPLLHIGLC 147
            ..|....|::|:    ...|..|:.:..:...|.|...:.....|...||       |.:.:.:|
Worm   131 SAGAFTECKSVS----MHSTSLNRTIRGDYYRILFDIKMRPNSFNDSCQL-------PQIGVDIC 184

  Fly   148 LPASCDVPEVEQLIRKSM--AKEESFHCWDMDAKLAYAKKPELKTNFFDSGAVQIFFVVLGVTLL 210
            ||.||...::....|:::  .||.|..|        ..:....:|..|..|.    :||  |||:
Worm   185 LPWSCRNEDLTDYFREALGATKELSPVC--------SVRNVNGRTPGFTFGT----YVV--VTLI 235

  Fly   211 LTLAATSGLG--------------KYSR----------ILACFDFADNWRLAWKPVNPSQENRPV 251
            |::.|||.:.              .|.|          |...|....|.:..:|....::|.: |
Worm   236 LSIIATSIVSCTVDYYFQNRRSKIDYERMEGSSNVGWKIFMAFSLYRNVKEIFKMKQCNKEGQ-V 299

  Fly   252 NGLRVLTAFSLIGVHVIWYKYFSVDPSVEMLGKLSSMTM------------RHTYWPTM------ 298
            ..|..:...|.:.|               :||..::|.:            ..||...:
Worm   300 TSLNCIRTISTVWV---------------ILGHCAAMLILICTNPVDLLDFTKTYMGALLVNAYF 349

  Fly   299 -VEIFFVVSGYLTVLNFIRDEQLQKD---IASDGILGNMRRYLREFIHRYCRLAPLQFVIVL-MG 358
             |:.||.:|.:|  |:|:..:||||.   :.|.|      .::..::||..||:|..::.:| :.
Worm   350 AVDTFFFISAFL--LSFLWFKQLQKQRKALISPG------GWMMFYVHRIARLSPAYYIAILFVT 406

  Fly   359 VVVIEYQRQVSVMQITDPQDELCRLNAVRNVFFIQNLFPIQFMCGSWTWSLGCDMQLHMTAMLLL 423
            .|.|...|.:........||:.|:.|...|:.:|:|:...:.:|...:|.|..|:||::.:.:||
Worm   407 FVYIRMLRDMPAFMSPAIQDDTCQQNYWLNLLYIENIVDTKNICYVISWYLATDLQLYLMSPILL 471

  Fly   424 FMHTKHPNMVKWIVRLLVVISALFSIVFMEVNEVGANFEEM------------------YHTNE- 469
            ....           :...:..||:.|...|.....|..::                  |:.||
Worm   472 LSFA-----------IGGAVFGLFASVVALVASTAFNAYQIFFWYFPPTDYPLGPKDPRYNENER 525

  Fly   470 ----WSYMSPLIRMLAYIIGGSYAFFQVKGTGTP-------FDLVMPNWWIRLGAIACI------ 517
                |:|.:||||...||:|....:|..|   .|       .|.:|  |.:.||::..:
Worm   526 RYDVWNYYNPLIRCQIYIMGLVLGYFMRK---VPKININPWVDRIM--WVLSLGSMVFVVLVIQD 585

  Fly   518 -----GWLARQVTMDQLPAISIILSFMVVLRILVSTAASHLIICGTKPDNSDSYAPTRWLLALLQ 577
                 ||...|..:           :....|:|...|.|.::|        .:|.....:...:.
Worm   586 YSSGDGWTPVQTAL-----------YSCFSRVLWGFAMSWIVI--------STYYRKGLIRDFMS 631

  Fly   578 SEQVQRISKFTYAIYLLNPIVIMYVYHSFSNEVYPDNTMMIML--AISCSVVCYLWAIVMTVLFE 640
            ......:::.::..||::.:|:.|.:....:|:|........|  .|..:.:.::.||..:.:||
Worm   632 LSFWTPLARLSFCAYLVHWMVLGYFFGRNHSELYFSTLSYFFLDTVIPVTALSFVIAIFWSSMFE 696

  Fly   641 IPFNRLTSVMINSRSSP 657
            |||.::..:::....:|
Worm   697 IPFAKIEGLLLGRSGTP 713

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12990	NP_573233.1	NRF	61..162	CDD:214781	21/114 (18%)
		Acyl_transf_3	251..637	CDD:280013	90/451 (20%)
		OafA	295..660	CDD:224748	87/417 (21%)
oac-39	NP_001300160.1	NRF	109..218	CDD:214781	25/127 (20%)
oac-39	NP_001300160.1	OafA	297..685	CDD:224748	88/446 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161202
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850