Protein Alignment CG12990 and oac-46

DIOPT Version :10

• Sequence 1: NP_573233.1
• Gene: CG12990 / 32747
• FlyBaseID: FBgn0030859
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: NP_495886.2
• Gene: oac-46 / 174415
• WormBaseID: WBGene00011768
• Length: 676
• Species: Caenorhabditis elegans
• Alignment Length: 735
• Identity: 156/735 - (21%)
• Similarity: 277/735 - (37%)
• Gaps: 161/735 - (21%)

  Fly     2 LLVLLLLQIIAALGDVDNCEPKSLAKDLIEMVPQRENTTLS-KCEEQLLELRRAWQDHQSWALKA 65
            |.:|||...||:.|..:..||     .:::.:.:.:...|| ||::.|..:.....|.::...:.
 Worm     5 LYLLLLSPAIASAGLEEYDEP-----FILQFINRSQTLDLSLKCKQSLALVYDYLNDIETLTDQK 64

  Fly    66 I-----DASGEGYANFMMGQRAWLGNRFTCRAVNEPMLQDMTIKNQRLLREMSPIQFHYLVAYIE 125
            |     .|:|.........|..|:...:.|           .:.....:...|....||...:.:
 Worm    65 ICYFESFATGPNDLFLSRDQDRWVYKGYEC-----------LLSAGETVYSKSEHPMHYCYTHDD 118

  Fly   126 SNSPWQLEVTIKANPLLHIGLCLPASCDVPEVEQLIRKSMAKEESFHCWDMDAKLAY--AKKP-- 186
            ...        |..|...:  |:|:.| ..|.::|:.:          |   .::.:  |.:|
 Worm   119 DKD--------KRVPAFSV--CIPSPC-ADENQKLLEE----------W---RRITHPEATEPIT 159

  Fly   187 --------------ELKTNFFDSG-AVQIFFVVLGVTLLLTLAATSGLGKYSRILACFDFADNW- 235
                          ||.....|.| .:.:..:|:..|:...:.........:|||..|....|.
 Worm   160 FTACTRSRHEKQWFELPVPIADFGFNMSLAMLVVMATIFHNMRGEDAKSWSARILLAFSAKTNLK 224

  Fly   236 RLAWKPVNPSQENRPVNGLRV-LTAFSLIGVHVIWYKYFSVDPSVEMLGKLSSMTMRHTYWPT-- 297
            :|...|.:|......:.|||. ...::|||...|:.:.:.  .:||.. |.|.:......|.|
 Worm   225 KLIALPKDPQSCITCLLGLRFGSMVWTLIGHSFIFVQAYM--ENVEDF-KNSMVDNFFNQWITNF 286

  Fly   298 --MVEIFFVVSGYLTVLNFIRDEQLQKDIASDGILGNMRRY-LREFIHRYCRLAPLQFVIVLMGV 359
              .|::|..:.|  |||::....:..|:.:.:........| |:.:.||..||.| .::..|:.|
 Worm   287 TLSVDVFLTLGG--TVLSYSWFRKWLKNTSEEEPTWTSWGYWLKFYRHRVVRLYP-AYLYTLLAV 348

  Fly   360 VVIEYQRQVSVMQI------TDPQDELCRLNAVRNVFFIQNLFPIQFMCGSWTWSLGCDMQLHMT 418
            .:     ::||...      |||..: |.....:||.|:.::...|  |..|||.:|.:...::.
 Worm   349 TL-----RISVTHFHPMWPPTDPAIQ-CPKYWWQNVLFVNSILDNQ--CMPWTWYIGTEFIYYLL 405

  Fly   419 AMLLLFMHTKHPNMVKWIVRLLVVISALFSIVFMEVNEVGANF---------EEMYHTNEWS--- 471
            :.:.|....|.|. :.:|:..:|:   :||......:.|..||         .||::.|...
 Worm   406 SPIFLLTLRKAPK-IGFILCFVVI---MFSAGLNVESIVRNNFPPTQFLWKQPEMFNPNFIQHHL 466

  Fly   472 --YMSPLIRMLAYIIG-------GSYAFFQVKGTGTPFDLVMPNWWIRLGAI---------ACIG 518
              |:.|..|:..|:||       ..|....||...:. ..::..|.:.|..|         |..|
 Worm   467 ELYIKPQYRIGPYLIGILLGYQLARYQRIPVKPQQSN-KYIISMWSVALVGILFGLYGLYPALQG 530

  Fly   519 WLARQVTMDQLPAISIILSFMVVLRILVSTAASHLI-ICGT---KPDNSDSYAPTRWLLALLQSE 579
            |       |.:...:..|.:..:.|.:.|...:.|| ||.|   .|.|           ..|.|.
 Worm   531 W-------DSIAWRAYHLLYGALHRDIFSIGIAFLIYICHTGIGGPVN-----------VFLSSN 577

  Fly   580 QVQRISKFTYAIYLLN--PIVIMYVYHSFSNEVYPDNTMMIMLAISCSV---VCYLWAIVMTVLF 639
            ....::..:::.||.:  |:|:.|:...|  .:| .|| .|.|.|.|.|   :.|.:||:.|::.
 Worm   578 FFLPLANLSFSAYLFHMIPVVLTYMLVPF--PIY-FNT-QIPLFIHCFVQLLITYFFAIICTMVS 638

  Fly   640 EIPFNRLTSVMINSRSSPAK 659
            |:|...:..:::   :||.|
 Worm   639 ELPALNIERLLL---ASPPK 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12990	NP_573233.1	NRF	44..161	CDD:466307	18/121 (15%)
		OafA	241..658	CDD:441440	108/467 (23%)
oac-46	NP_495886.2	OafA	242..653	CDD:441440	105/454 (23%)