DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12990 and oacyl

DIOPT Version :9

Sequence 1:	NP_573233.1	Gene:	CG12990 / 32747	FlyBaseID:	FBgn0030859	Length:	663	Species:	Drosophila melanogaster
Sequence 2:	XP_021324686.1	Gene:	oacyl / 100002566	ZFINID:	ZDB-GENE-090710-2	Length:	676	Species:	Danio rerio

Alignment Length:	741	Identity:	153/741 - (20%)
Similarity:	259/741 - (34%)	Gaps:	235/741 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 NTTLSKCEEQ----LLELRRAWQDHQSWALKAIDASGEGYANFMMGQRAWLGNRFTCRAVNEPML 98
            |.:| ||.:.    |:||::  :....:|:...||.|:      :|.....||      ||.|
Zfish    24 NVSL-KCVDDTMGFLMELQK--ETPSKFAVIMYDAFGK------IGSDVEGGN------VNRP-- 71

  Fly    99 QDMTIKNQRLLREMSPIQ-----FHYLVAYIESNSPWQLEVTIKANPLLHIGLCLPASCDVPEVE 158
                    ..|||...::     ..|...:::.:   ::|        ..:|:|:|.||...||:
Zfish    72 --------GSLRECLSVEGPGFRGQYCQVFLKQD---KVE--------YFVGVCVPDSCTDSEVQ 117

  Fly   159 QLIRKSMAKEESFHCWDM------------DAKL------AYAKKPELKTNFFDSGAV------- 198
            .|:     ..|:|....|            |:.|      .::..|.:     |..|:
Zfish   118 TLV-----IHEAFQKQQMSLLPSVPSILIPDSTLGIFMTQCHSDSPNI-----DLSAIVCLSVCC 172

  Fly   199 ---------QIFFVVL------GVTLLLTLAATSGLGKYSRILA---------CFDFAD------ 233
                     .||..::      .|..::.||.||...:|..:|.         |....|
Zfish   173 ALLALPLIASIFVALIKRKQMREVAPVVGLAQTSNSKQYGTVLTNGSANQNKECSPDLDTTQTKT 237

  Fly   234 ---------------NWRLAWKPVNPSQ----------ENRPVNGLRVLTAFSLIGVHVIWYKYF 273
                           :|...:...|.||          ....:||:|:|:.|.:|..|.:.:..:
Zfish   238 QNAESKQQSLSKTVVSWLQGFSVQNCSQGLLDTEGSGRSYSSLNGIRILSLFWIISGHTVHFSAW 302

  Fly   274 S-VDPSVEMLGKLSSMTMRHTYWPTMVE----IFFVVSG--YLTVLNFIRDEQLQKDIASDGILG 331
            | :|              ....|..|||    .....||  ||.|.:|:   .|...:::..:||
Zfish   303 SHLD--------------NEKRWKEMVENNPLYVLTFSGPVYLAVDSFL---VLGGLLSAKSLLG 350

  Fly   332 NMRR------------YLREFIHRYCRLAPLQFVIVLMGVVVIEYQRQVSVMQITDPQDELCRLN 384
            .:||            ||   ..|:.|:.||...||.:.:.:.....:.......:.|...|:..
Zfish   351 TIRRSDNTLSVGLVVNYL---FKRFKRIQPLHLFIVCLVISLFSVVPRGVFWFFAEDQVLSCKKY 412

  Fly   385 AVRNVFFIQNLFPIQFMCGSWTWSLGCDMQLHMTAMLLLFMHTKHPNMVKWIVRLLVVISA---- 445
            ...|:..|.||..|..:|..|||.|..|.|.:.|..||:|::..:...:..:..:|:::|:
Zfish   413 WWSNLLLINNLLTITDICAPWTWYLSIDFQFYATTPLLIFLYRMNKCALVVVSVVLLMLSSVTGA 477

  Fly   446 -LFSIVFMEVNEVGANFEEMYHTNEWSYMSPLIRMLAYIIG---GSYAFFQVKGTGTPFDLVMPN 506
             :.|.:.:.|::......|.|.  ::.|..|..|...|::|   |.|.      |.....|:...
Zfish   478 LITSFLHLPVHQPTTLAYESYF--QYYYNKPYTRYGPYLLGVLAGIYM------TTKKEALIKHQ 534

  Fly   507 WWIRLGAIACIGWLARQVTMDQLPAISIILSFMVVLR-ILVSTAASHLIICGTKPDNSDSYAPTR 570
            |.      |.||||.      .|..:::::....||| :....:..|.|..|..        .:.
Zfish   535 WQ------AVIGWLC------SLSVMALLVGLAYVLRDVPPHLSIPHAIYQGIH--------RSL 579

  Fly   571 WLLAL------------------LQSEQVQRISKFTYAIYLLNPIVIMYVYHSFSNEV---YPDN 614
            |.|||                  |.......:|..::|.||::||:|  :.::...|:   |.|.
Zfish   580 WALALIWIILACEEGYGGFVDTFLSLSLWAPLSNISFACYLIHPIII--ILYNGKQEITMHYTDF 642

  Fly   615 TMMIMLAISCSVVCYLWAIVMTVLFE 640
            . ...|.:...|:......|:|||.|
Zfish   643 N-FFYLFLGHLVLSIFIGYVLTVLIE 667

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12990	NP_573233.1	NRF	61..162	CDD:214781	23/105 (22%)
		Acyl_transf_3	251..637	CDD:280013	96/434 (22%)
		OafA	295..660	CDD:224748	91/394 (23%)
oacyl	XP_021324686.1	NRF	48..120	CDD:214781	22/104 (21%)
oacyl	XP_021324686.1	OafA	273..668	CDD:224748	100/446 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920