Protein Alignment beta-Spec and Ehbp1

DIOPT Version :9

• Sequence 1: NP_001259660.1
• Gene: beta-Spec / 32746
• FlyBaseID: FBgn0250788
• Length: 2308
• Species: Drosophila melanogaster
• Sequence 2: NP_995865.2
• Gene: Ehbp1 / 36912
• FlyBaseID: FBgn0034180
• Length: 1141
• Species: Drosophila melanogaster
• Alignment Length: 1012
• Identity: 197/1012 - (19%)
• Similarity: 332/1012 - (32%)
• Gaps: 381/1012 - (37%)

  Fly   127 ENIGSHDIVDGNASLNLGLIWTIILRFQIQDITIEEVDNKETKSAKDALLLWCQMKTAGYHNVNV 191
            |:|||.....|:.:.:|..:..|:|              ||....:| ||.||:..|..|.||.|
  Fly   431 ESIGSCFSTSGSLNNSLKPVEKIVL--------------KENTPGQD-LLEWCKEVTKDYPNVKV 480

  Fly   192 RNFTTSWRDGLAFNAIIHKHRPDLVQFEKLSKTNAIHNLNNAFDVAEDKLGLAKLLDAEDV-FVE 255
            .|.|||||:|:||.||||...|:|:...|||..:.:.|....||.|| .||:.::::..|: .:.
  Fly   481 TNLTTSWRNGMAFCAIIHHFVPELIDMSKLSAHDVVGNCRIGFDAAE-SLGIPRVIEPRDMNMLT 544

  Fly   256 HPDEKSIITYVVTYYHYFSKLKQETVQGK--RIGKVVGIAMENDKMVHDY--ENFTSDLLKWIET 316
            .||:.:::||:.....:|:        ||  :|.::...|.|:..::.||  :|.:.:.:.:...
  Fly   545 VPDKLAVMTYLHQLRAHFT--------GKQLKIEQIGSTADESSYVIGDYKSDNLSQNRINFSHP 601

  Fly   317 TIQSLGEREFENSLAGVQGQLAQFSNYRTIEKPPK----FVEKGNLEVLLFTLQSKMRAN----- 372
            ....|.:..|:..:.| ..:..|.|  .|.:|..|    :..|..|:.:|...:.|...|
  Fly   602 KSLLLHQNSFDEEING-SNKSEQLS--PTSKKDVKNLILYNSKNILDKVLSPTKDKNSINASQHA 663

  Fly   373 NQKPY-----TP--------------KEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQ 418
            ||.|.     ||              ||...|:.|:.     :.|..||:    :.|:.|.:...
  Fly   664 NQSPMLSCQTTPPQDESLDKGSQPGGKENSSITTIDP-----QAASEERQ----QRLLEQARRLI 719

  Fly   419 LAARFDRKASMRETWLSENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDE 483
            |..|.....|:......:.:|.:|..:.|.:....| .|||.|..|..
  Fly   720 LETRVKSGGSIESPTRPKLERTISPIHNGAEEFYAE-HAKKLELKEPG----------------- 766

  Fly   484 LESERYHDVKRILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLM 548
            ..|.|..|.|        |::.:..::|         .:|.:.::...::.||...:|.:::
  Fly   767 SPSHRLSDPK--------VLQSFNAIVE---------RVSPKHEKRGDKLSYIDSELEALER--- 811

  Fly   549 TDDYGKHLMGVEDLLQKHSLVEADIN-ILG----ERVKVVVQNSQKFLSDDPESYKPCDPEIIVS 608
                     ..|.:.||.|.:||.:. ::|    ...:...:||..||
  Fly   812 ---------EQEAIDQKASNLEAKLRAVMGGNPSNNRRGGARNSNPFL----------------- 850

  Fly   609 RVQQLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLM 673
                      .|:|.::.                                     |.|:..:.|:
  Fly   851 ----------RLIRNSIG-------------------------------------GGDVIRIKLL 868

  Fly   674 LSKHKALE--------------SEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLK------- 717
            .|..::|.              ||....|....:|...|.||.|       |::.|.:
  Fly   869 DSDDESLFGGGAGSGGGRSGACSEDDDRDTSSDSVCNSGDELHT-------RLRPRPRSHSCFVN 926

  Fly   718 ----EILNKWDHLLDLTKYRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQS 778
                ..:|...||      |...:.:.|.|           ..|||               :..|
  Fly   927 KNHQSTINTPAHL------RPHHVHHVVPY-----------THMLD---------------SSPS 959

  Fly   779 LLKKHKDVADELKNYAEVIDALHKQAESLKLNEAEKANVDKRLEAIDNRYKELTELAKLRKQRLL 843
            .|...:...|.|...::..:.|           |..||               ...|.||:|
  Fly   960 ALSSQQSSCDNLPACSDDDEVL-----------AVAAN---------------GRAASLRRQ--- 995

  Fly   844 DALSLYKLMSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMNANASRVAVVNQL 908
                                               :|    :||.....:|..:
  Fly   996 -----------------------------------QD----RHRRRRQRRERRS----------- 1010

  Fly   909 ARQLLHVEH-PNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDKK 972
                 |:.| ||..|..|.:..|..:|.||..|..|.:
  Fly  1011 -----HLCHTPNHCETEETEEQLLSQWFTLVNKKNALL--------------------------- 1043

  Fly   973 RILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPEEAKIIRERIAQI 1037
            |...:.:.||.:    ..|:|:.:.::::|           |.|.|:||....|.:..:||:...
  Fly  1044 RRQMQLNILEQE----KDLERKYTMLNQEL-----------RAAQSVEDWRKTEVQREKERLLLE 1093

  Fly  1038 ELIW-----EQLTQMLKERDSKLEEAGDLHRFLRDLD 1069
            ||:.     :||.|.|..::..:|:..::.|.|..:|
  Fly  1094 ELMTIVDKRDQLVQHLHNQEIAIEDDQEIARKLEHVD 1130

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
beta-Spec	NP_001259660.1	CH	51..149	CDD:278723	6/21 (29%)
		CH	170..269	CDD:278723	40/99 (40%)
		Spectrin	298..408	CDD:278843	28/139 (20%)
		SPEC	422..521	CDD:197544	17/98 (17%)
		SPEC	525..740	CDD:238103	35/244 (14%)
		SPEC	639..846	CDD:238103	36/231 (16%)
		SPEC	848..1058	CDD:238103	37/215 (17%)
		SPEC	955..1169	CDD:238103	24/120 (20%)
		SPEC	1170..1380	CDD:238103
		SPEC	1386..1484	CDD:197544
		SPEC	1488..1699	CDD:238103
		SPEC	1594..1806	CDD:238103
		SPEC	1807..2015	CDD:238103
		Spectrin	2018..>2078	CDD:278843
		PH	2167..2275	CDD:278594
		PH_beta_spectrin	2167..2274	CDD:269975
Ehbp1	NP_995865.2	NT-C2	12..165	CDD:287345
		CH	460..562	CDD:237981	40/103 (39%)
		DUF3585	<1027..1122	CDD:288945	27/136 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910