Protein Alignment RhoGAPp190 and AT5G12150

DIOPT Version :10

• Sequence 1: NP_001259658.1
• Gene: RhoGAPp190 / 32743
• FlyBaseID: FBgn0026375
• Length: 1621
• Species: Drosophila melanogaster
• Sequence 2: NP_196776.1
• Gene: AT5G12150 / 831088
• AraportID: AT5G12150
• Length: 827
• Species: Arabidopsis thaliana
• Alignment Length: 690
• Identity: 122/690 - (17%)
• Similarity: 212/690 - (30%)
• Gaps: 210/690 - (30%)

  Fly   649 AIDVYSSGLICVYSN---QQSFETLKDNLERTLLCNLELEDKFENLPIVLVYQPQD----LKENE 706
            |:.:..:|:....:|   :.||.:.:|        ...|:......||:|..:..|    ..|..
plant   131 ALVIGQNGIFRTEANNTIEASFNSWRD--------QRPLKSSVVGRPILLALEEIDGSPSFLEKA 187

  Fly   707 VEYLRNEGMRLSEMLH--CDFIDHTQNHQKY---------------VYDILNIVILSLKLTEMKS 754
            :::|...|.::..:|.  .|..:..:..|:|               |.|.:..|:..|..:
plant   188 LQFLETYGTKVEGILRQSADVEEVERRVQEYEQGKTEFSPEEDPHVVGDCVKHVLRQLPSS---- 248

  Fly   755 YEPYPSNHTDLRILCCIFCGDQYDIENIVQPLVEESTLVKANE------HSIIVDVFIGDAKRRV 813
              |.|::       ||....:.|.|:.              ||      .|.|::.|....:|.:
plant   249 --PVPAS-------CCTALLEAYKIDQ--------------NEARVNSLRSAIIETFPEPNRRLL 290

  Fly   814 EFILSSYHGTSQYRDELIHGYIYFYSTKRRSSLA-----------------------------NL 849
            ..:|...|..:.:..|           .|.:|.|                             :.
plant   291 LRMLKMMHTITSHSSE-----------NRMTSSAVAACMSPLLLRPLLAGECDLEGFDTLGDNSA 344

  Fly   850 SILAAQNANIPLQIIAVTESGGVNAFFNSDICQFLITEGNAVADRFKGSFMTFSADQYVKFAFYN 914
            .:|||.||....|.|               :...|...||.:.|...|...| |.|.::.
plant   345 QLLAAANAANNAQAI---------------VTALLEDYGNMINDEGLGRCST-STDSHIG----- 388

  Fly   915 PFLKTAWDNKYEVENLHVE----ESITLDSGEGTLENSVNQMPRPPPRHESYMLSNTLGTDGSGS 975
               .:..:|..:.|.:.|:    .::.::.||...:|.| .:.|.|.....|..|:.....|.|.
plant   389 ---DSGPENSSDEEEIVVKHPDLHTLDIEEGETDDDNDV-LLSRKPSESSDYAGSDLYDYKGFGV 449

  Fly   976 ENYEMAPTRSLNSLNEERDIS------LDEIYDDNE-----KPKHLHQRFQIFPPPTTPPEPAPP 1029
            |:.:....|.::...|..|.|      ::|...|.|     ..::.:|..:...|..||..|
plant   450 EDSDAESPRDIHCSVESTDFSARVKKHIEEPIKDIEVSSVSPTENCYQSGREAIPSVTPSTP--- 511

  Fly  1030 DHQLITCTYKSQFVSASESSLEEITSDVSGSKDSLATHDAEWLEDKSDGRRNMNKNLIWNNF--S 1092
               |....|        .:|.|:..|..:||....:...:.|      ||.|..|.....:|  |
plant   512 ---LTALRY--------TTSAEKPASKTTGSSTVNSKRSSSW------GRGNGKKTPAKGSFDSS 559

  Fly  1093 GSTHAYTTGRRHIDSNLNKIRPKGPSQTLKVGEAPSRNCPAMSSSTFTLPTQQPGKLNMKNFQLV 1157
            |:.........|:...|.:...|.......:..:..|...|:......| .|..|:| .:..|..
plant   560 GNDELLIQRLEHMKDELRQRIAKEAKGNAALQASLERRKQALHERRLAL-EQDVGRL-QEQLQAE 622

  Fly  1158 SDAVAKMNFTGSGSGSGSGSGSGSTGLGLGLGSGSGCMGDSFLEPVDKDGKRYDHAQLDGEDEDS 1222
            .|..:.:.                  :||.:..|                      |...:..||
plant   623 RDLRSALE------------------VGLSISCG----------------------QFSSQAADS 647

  Fly  1223 EELAEYEQIYENE-DCTESDSCASSTERRVRQQNAYYKAS 1261
            :..||.|:|...| |........:....::.||..::.:|
plant   648 KTRAELEEIALAEADVARLKQKVAELHHQLSQQRQHHLSS 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAPp190	NP_001259658.1	P-loop containing Nucleoside Triphosphate Hydrolases	<148..238	CDD:476819
		RhoGAP-FF1	254..333	CDD:465153
		pseudoGTPaseD_p190RhoGAP	598..748	CDD:412064	21/122 (17%)
		RhoGAP_p190	1411..1611	CDD:239838
AT5G12150	NP_196776.1	PH	19..116	CDD:459697
		RhoGAP	181..325	CDD:459875	29/181 (16%)
		COG4913	<566..>729	CDD:443941	26/164 (16%)
		Lzipper-MIP1	600..678	CDD:464163	19/119 (16%)