Protein Alignment CG5800 and DDX31

DIOPT Version :9

• Sequence 1: NP_573230.1
• Gene: CG5800 / 32742
• FlyBaseID: FBgn0030855
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: XP_011517223.1
• Gene: DDX31 / 64794
• HGNCID: 16715
• Length: 787
• Species: Homo sapiens
• Alignment Length: 621
• Identity: 194/621 - (31%)
• Similarity: 296/621 - (47%)
• Gaps: 123/621 - (19%)

  Fly     9 PGKPGSRFKPGSGTFKGAGGGRK----------SGDNSQKRPRQEINKSRLAATEAEIQDLKTKY 63
            |.|..| .|....|||  |..:|          :.|.:|:. ||.|..|.|.....:|.:|..
Human   158 PAKKTS-VKETQRTFK--GNAQKMFSPKKHSVSTSDRNQEE-RQCIKTSSLFKNNPDIPELHR-- 216

  Fly    64 AEIDATAIKKFAQFPLSKKTQ-KALAESKF----VHP---------------TQVQRDSIGPALQ 108
                          |:.|:.| |....:.|    :||               |.||:.||...|:
Human   217 --------------PVVKQVQEKVFTSAAFHELGLHPHLISTINTVLKMSSMTSVQKQSIPVLLE 267

  Fly   109 GKDVLGAAITGSGKTLAFLIPVLEHL--FMNKWSRTDGVGAIIISPTRELAYQIFETLKKVGKHH 171
            |:|.|..:.||||||||:.|||::.|  ..:|..|:||..|:::.||||||.|.|:|::|:.|..
Human   268 GRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPF 332

  Fly   172 DFSA-GLIIGGKNLKFERTRMDQ-CNILICTPGRLLQHMDENPLFNTSTMEMLVLDEADRCLDMG 234
            .:.. |:::||:..|.|:.|:.: .||||.|||||:.|:......:.|.:..||.|||||.||:|
Human   333 TWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLG 397

  Fly   235 FQKTLNSIIENFP---PVRQTLLFSATQTNTVQDLARLNLKDPVYV-----GYGGATPREE---- 287
            |:|.:..|:....   ..||.:|.|||.|..|..||.::|.|||.:     .:....|:::
Human   398 FEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQE 462

  Fly   288 ---PSASTKKTPNTAVLAVPELLQQSYVVLNLEDKITMLWSFIKNHLK----QKIIVFVASCKQA 345
               |.|..|...    .|:||.|:|...|:..:.::..|.:||....|    ||::||.:||:..
Human   463 VCPPPAGDKLDS----FAIPESLKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVFFSSCELV 523

  Fly   346 KYLYEIFCKL---RPGSP-------------LLALYGTLHQDRRIAIYEDFLRKSHVVMFSTDVA 394
            ::.|.:|.:.   ..|:|             .|.|:|.:.|:.|.|::::|......|:..||||
Human   524 EFHYSLFLQTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVA 588

  Fly   395 SRGLDFPAVNWVVQLDCPEDVSQYIHRAGRSARNKTRGECLLVLTPSEEEYMISALKEQLNI--- 456
            :||||.|.|.|:||.:.|...::||||.||:||....|..||:|.|||.||:.|....::|:
Human   589 ARGLDLPQVTWIVQYNAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEI 653

  Fly   457 ---DIRCV------------------QIDPKKLFSPRVKIEAFLAQF---PELRAT-AQRAFLSY 496
               ||.||                  .:.|:::......::.....:   .|.|.: |::|..|:
Human   654 KMEDILCVLTRDDCFKGKRWGAQKSHAVGPQEIRERATVLQTVFEDYVHSSERRVSWAKKALQSF 718

  Fly   497 IK--SVFLMRNKRLFNVFSLDLDAFAQSLGLAVTPR 530
            |:  :.:....|.:|:|.||.|...|:|.||...||
Human   719 IQAYATYPRELKHIFHVRSLHLGHVAKSFGLRDAPR 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5800	NP_573230.1	PRK01297	2..471	CDD:234938	176/554 (32%)
		DEADc	74..277	CDD:238167	88/229 (38%)
		HELICc	311..437	CDD:238034	47/145 (32%)
		DUF4217	474..530	CDD:290667	16/61 (26%)
DDX31	XP_011517223.1	PRK01297	126..666	CDD:234938	175/531 (33%)
		DEADc	232..444	CDD:238167	84/211 (40%)
		HELICc	481..631	CDD:238034	49/149 (33%)
		DUF4217	693..754	CDD:290667	16/60 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920