DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG5800 and Ddx56

DIOPT Version :9

Sequence 1:NP_573230.1 Gene:CG5800 / 32742 FlyBaseID:FBgn0030855 Length:826 Species:Drosophila melanogaster
Sequence 2:NP_080814.1 Gene:Ddx56 / 52513 MGIID:1277172 Length:546 Species:Mus musculus


Alignment Length:555 Identity:144/555 - (25%)
Similarity:243/555 - (43%) Gaps:96/555 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    74 FAQFPLSKKTQKALAESKFVHPTQVQRDSIGPALQGKDVLGAAITGSGKTLAFLIPVLEHLFMNK 138
            |....|..:..:|:.:..:..||.:|..:|..||:|||:|..|.||||||.|:.||:|:.|...|
Mouse     9 FEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQSLLHKK 73

  Fly   139 WS---RTDGVGAIIISPTRELAYQIFETLKKVGKH--HDFSAGLIIGGKNLKFER-TRMDQCNIL 197
            .:   ....|..:::.||:|||.|....::::..:  .|.....:...::...:| ..|::.:::
Mouse    74 ATGPVMEQAVRGLVLVPTKELARQAQAMIQQLAAYCARDVRVANVSAAEDSASQRAVLMEKPDVV 138

  Fly   198 ICTPGRLLQHMDENPLFNTSTMEMLVLDEADRCLDMGFQKTLNSIIENFPPVRQTLLFSATQTNT 262
            :.||.|:|.|:.:|.|....::|:||:||||.....||:..|.|::.:.|.:.|..|.|||....
Mouse   139 VGTPSRVLSHLQQNTLKLRDSLELLVVDEADLLFSFGFEDELKSLLCHLPRIYQAFLMSATFNED 203

  Fly   263 VQDLARLNLKDPVYVGYGGATPREEPSASTKKTPNTAVLAVPELLQQSYVVLNL-EDKITMLWSF 326
            ||.|..|.|.:||                |.|...:. |..|:.|||..||... |||..:|::.
Mouse   204 VQTLKELVLHNPV----------------TLKLQESQ-LPGPDQLQQFQVVCETEEDKFLLLYAL 251

  Fly   327 IK-NHLKQKIIVFVASCKQAKYLYEIFCKLRPGSPLLALYGTLHQDRRIAIYEDFLRKSHVVMFS 390
            :| :.::.|.::||.:.::. |...:|.: :...|...|.|.|....|..|...|.:..:..:.:
Mouse   252 LKLSLIRGKALLFVNTLERG-YRLRLFLE-QFSIPSCVLNGELPLRSRCHIISQFNQGLYDCVIA 314

  Fly   391 TDV---------------------------ASRGLDFPAVNWVVQLDCPEDVSQYIHRAGRSARN 428
            ||.                           .:||:||..|:.|:..|.|.....|:|||||:||.
Mouse   315 TDAEILGPQVKGKRRGRGSKGNKASDPESGVARGIDFHHVSAVLNFDLPPTAEAYVHRAGRTARA 379

  Fly   429 KTRGECLLVLTPSEEEYMISALKEQLNIDIRCVQIDPKKLFSPRVKIEAFLAQFPE-LRATAQRA 492
            ...|..|..:.|:|:.: :..:::.|:.:.....:.|.:.  ...:||:|..:..: :|:..::|
Mouse   380 NNPGIVLTFVLPAEQPF-LGKIEDLLSGEGEAPILLPYQF--QMEEIESFRYRCRDAMRSVTKQA 441

  Fly   493 F----LSYIKSVFLMRNKRLFNVFS---LDLDAFAQSLGL-----------------------AV 527
            .    |..||.. |:.:::|...|.   .||......|.|                       .|
Mouse   442 IREARLKEIKEE-LLHSEKLKTYFEDNPRDLQLLRHDLPLHPAVVKPHLGHVPDYLVPAALRGLV 505

  Fly   528 TPR-----VPFLEKF--LWRQKQLQQQKEQGDNAK 555
            .||     |||..|.  :..|..|:..|.:|...|
Mouse   506 HPRKKRRKVPFSRKAKKVKAQNPLRDFKHRGKKPK 540

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5800NP_573230.1 PRK01297 2..471 CDD:234938 117/431 (27%)
DEADc 74..277 CDD:238167 67/208 (32%)
HELICc 311..437 CDD:238034 39/154 (25%)
DUF4217 474..530 CDD:290667 16/86 (19%)
Ddx56NP_080814.1 Q motif 7..35 5/25 (20%)
SrmB 9..544 CDD:223587 144/555 (26%)
P-loop_NTPase 9..219 CDD:304359 68/225 (30%)
DEAD box 166..169 2/2 (100%)
HELICc 234..388 CDD:238034 39/155 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 324..344 0/19 (0%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 508..546 10/33 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D973872at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

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