DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5800 and ddx51

DIOPT Version :9

Sequence 1:	NP_573230.1	Gene:	CG5800 / 32742	FlyBaseID:	FBgn0030855	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	NP_001003864.1	Gene:	ddx51 / 445387	ZFINID:	ZDB-GENE-040927-28	Length:	652	Species:	Danio rerio

Alignment Length:	469	Identity:	122/469 - (26%)
Similarity:	195/469 - (41%)	Gaps:	77/469 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 TKYAEIDATAIKKFAQFPLSKKTQKALAESKFVHPTQVQRDSIGPAL-------QGKDVLGAAIT 118
            |...::....|:.|  ||:..:...|:.|            |:|..|       :.:||..:|.|
Zfish   199 TLLRKLQTNGIQSF--FPVQAEVIPAILE------------SVGSGLLVGPGGYRPRDVCVSAPT 249

  Fly   119 GSGKTLAFLIPVLEHLFMNKWSRTDGVGAIIISPTRELAYQIFETLKKVGKHHDFSAGLIIGGKN 183
            ||||||||:|||::.|......:   |.|:.:.||:|||.|:........:.......:|.|.|:
Zfish   250 GSGKTLAFVIPVVQALSKRVVRQ---VRALAVLPTKELAQQVSNVFSAYTEGSSLKVVMITGQKS 311

  Fly   184 LKFERTRMDQ---------CNILICTPGRLLQHMDENPLFNTSTMEMLVLDEADRCLDMGFQKTL 239
            ...|:|.:.:         .:|::.|||||:.|:::|..|:...:..|::|||||.:|...|..|
Zfish   312 FAAEQTALSEIRGGVSHSMADIVVATPGRLVDHINKNSSFSLQHLRFLIIDEADRMIDSMHQSWL 376

  Fly   240 NSIIENF--------------------------PP--VRQTLLFSATQTNTVQDLARLNLKDPVY 276
            :.:.:..                          ||  ..|.||||||.|...:.|..|:|..|..
Zfish   377 SQVTKAVYSTPGETHTSVFRRTVPGPITAASLSPPQIPLQKLLFSATLTQNPEKLQLLDLHQPRL 441

  Fly   277 VGYGGATPREEPSASTKKTPNTA----VLAVPELLQQSYVVLNLEDKITMLWSFIKNHLKQKIIV 337
            .           |::...|.|.|    ....|:.|.:.||......|..::..|:........:.
Zfish   442 F-----------SSTHSLTDNPAQSQDTFHFPQGLSEYYVPCTFSKKPLIILHFLLRLKFSPALC 495

  Fly   338 FVASCKQAKYLYEIFCKLRPGSPLLALYGTLHQDRRIAIYEDFLRKSHVVMFSTDVASRGLDFPA 402
            |..|.:.|..|| :..||..|..:......|....|....:||.:....::.|||.|:||:|...
Zfish   496 FTNSREGAHRLY-LLVKLFGGVEVAEFSSKLSPGERQKTLKDFEKGKIPLLISTDAAARGIDING 559

  Fly   403 VNWVVQLDCPEDVSQYIHRAGRSARNKTRGECLLVLTPSEEEYMISALKEQLNIDIRCVQIDPKK 467
            |..|:..|.|:.:..||||.||:||....|.....|...:|:..:..:.:..:..|:...:.|:.
Zfish   560 VKCVINYDAPQYIRTYIHRVGRTARAGKAGLAFTFLLKVQEKRFLKMVSDAGSPGIQKQHVHPEA 624

  Fly   468 LFSPRVKIEAFLAQ 481
            |.|...:.|..||:
Zfish   625 LKSMESRYEQVLAE 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5800	NP_573230.1	PRK01297	2..471	CDD:234938	118/457 (26%)
		DEADc	74..277	CDD:238167	69/246 (28%)
		HELICc	311..437	CDD:238034	36/125 (29%)
		DUF4217	474..530	CDD:290667	3/8 (38%)
ddx51	NP_001003864.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..145
		P-loop_NTPase	195..439	CDD:304359	70/256 (27%)
		DEXDc	204..451	CDD:214692	72/274 (26%)
		Q motif	212..220		3/9 (33%)
		DEAD box	362..365		2/2 (100%)
		Helicase_C	475..586	CDD:278689	33/111 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010