Protein Alignment CG5800 and Ddx1

DIOPT Version :10

• Sequence 1: NP_573230.1
• Gene: CG5800 / 32742
• FlyBaseID: FBgn0030855
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_524212.2
• Gene: Ddx1 / 40457
• FlyBaseID: FBgn0015075
• Length: 727
• Species: Drosophila melanogaster
• Alignment Length: 572
• Identity: 128/572 - (22%)
• Similarity: 211/572 - (36%)
• Gaps: 194/572 - (33%)

  Fly    99 QRDSIGPALQGKDVLG---------AAITGSGKTL--AFLIP------------VLEHLFMN-KW 139
            |.|..|.|....||:|         .:.|.:|:.|  ||.:|            ||::..|. .:
  Fly   177 QFDDYGEAFGKADVIGCLLDLKNQEVSFTKNGQNLGVAFRLPDNLAKETFYPAVVLKNAEMQFNF 241

  Fly   140 SRTD-----GVG-----------------------------------AIIISPTRELAYQIFETL 164
            .:||     |.|                                   |||:.|:||||.|.:..:
  Fly   242 GKTDFKYAPGNGFVGACQAGPEHSKANPITGPAAGAPSAKPAPNAPQAIIMEPSRELAEQTYNQI 306

  Fly   165 KKVGKHH----DFSAGLIIGGKNLKFERTRMDQ-CNILICTPGRLLQHMDENPLFNTSTMEMLVL 224
            :|. |:|    :..:.|:|||..|:.::.::.| .:|::.|||| |:.|..:.|...:.....||
  Fly   307 EKF-KYHLSNPEVRSLLLIGGVRLEEQKAQLMQGTHIVVGTPGR-LEEMINSGLVLLTHCRFFVL 369

  Fly   225 DEADRCLDMGFQKTLNSIIENFPPVR------QTLLFSAT------------------------- 258
            ||||..|..|:.:.::.:.:..|.:.      |.::.|||
  Fly   370 DEADALLKQGYTELIDRLHKQIPKITSDGRRLQMVVCSATLHAFEVKKMAERLMHFPTWVDLKGE 434

  Fly   259 --QTNTVQDLARL----------NLKDPVYVGYGGATPRE--EPSASTKKTPNTAVLAVPELLQQ 309
              ...||..:..|          :|:.|  :|..|...|:  .|...:|:|.:.||    :||:.
  Fly   435 DAVPETVHHVVCLVDPQMDTTWQSLRQP--IGTDGVHDRDNVHPGNHSKETLSQAV----KLLKG 493

  Fly   310 SYVVLNLEDKITMLWSFIKNHLKQKIIVFVASCKQAKYLYEIFCKLRPGS--PLLALYGTLHQDR 372
            .|.|           ..|..|...:.|:|..:.:....| |.|.:.|.|.  ..:.|:|......
  Fly   494 EYCV-----------HAIDKHNMDRAIIFCRTKQDCDNL-ERFLRQRGGKHYSCVCLHGDRKPQE 546

  Fly   373 RIAIYEDFLRKSHVVMFSTDVASRGLDFPAVNWVVQLDCPEDVSQYIHRAGRSARNKTRGECL-L 436
            |....|.|.|:....:..||||:||||...:.:::.:..|:|.:.|:||.||..|.:..|..: |
  Fly   547 RKENLEMFKRQQVKFLICTDVAARGLDITGLPFMINVTLPDDKTNYVHRIGRVGRAERMGLAISL 611

  Fly   437 VLTPSE--------------------------------EEYMISALKEQLNIDIRCVQID----- 464
            |.|..|                                |..:::.:::.|||.|:  |:|
  Fly   612 VATVPEKVWYHGEWCKSRGRSCNNTNLTEVRGCCIWYNEPNLLAEVEDHLNITIQ--QVDKTMDV 674

  Fly   465 PKKLFSPRV------------------KIEAFLAQFPELRATAQRAFLSYIK 498
            |...|..:|                  ::...:.:..||...:|..||..:|
  Fly   675 PVNDFDGKVVYGQKNLRTGSGYEDHVEQLVPTVRKLTELELQSQSLFLKRLK 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5800	NP_573230.1	SrmB	71..493	CDD:440279	125/565 (22%)
		DEADc_DDX10	83..279	CDD:350699	64/291 (22%)
		DUF4217	474..530	CDD:464056	6/25 (24%)
Ddx1	NP_524212.2	DEAD-like_helicase_N	4..>73	CDD:475120
		SPRY_DDX1	91..242	CDD:293933	16/64 (25%)
		SrmB	283..613	CDD:440279	89/349 (26%)