DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5800 and mahe

DIOPT Version :9

Sequence 1:	NP_573230.1	Gene:	CG5800 / 32742	FlyBaseID:	FBgn0030855	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	NP_001284994.1	Gene:	mahe / 31707	FlyBaseID:	FBgn0029979	Length:	945	Species:	Drosophila melanogaster

Alignment Length:	508	Identity:	143/508 - (28%)
Similarity:	230/508 - (45%)	Gaps:	83/508 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QKPKGPGKPGSRFKPGSGTFKGAGGGRKSGDNS-------QKRPRQEINKSR------------- 48
            |:.|.|.......||.:|.  |..||.:|.:.:       .|..|.||.:.:
  Fly   129 QRGKNPTYAQRYQKPNNGA--GVAGGYQSNNYNAAALGMLSKEERAEIQREKAKNPGRNLVKPKW 191

  Fly    49 -----------------LAATEAEIQDLKTKYAEIDATA--------IKKFAQFPLSKKTQKALA 88
                             ||.:|.::.:::   .|::.|.        :..|.:..|.....:.:.
  Fly   192 ENLEPFLKDFYNIHPNTLAKSEQQVAEIR---RELEITVSGNELPHPVVSFEESSLPAHVIEEMK 253

  Fly    89 ESKFVHPTQVQRDSIGPALQGKDVLGAAITGSGKTLAFLIPVLEHL-FMNKWSRTDGVGAIIISP 152
            ...|..||.:|......||.|:|::|.|.||||||||:::|.:.|: ......|.:|..|::::|
  Fly   254 RQGFTKPTAIQSQGWPIALSGRDLVGIAQTGSGKTLAYMLPAIVHIGNQPPIIRGEGPIALVLAP 318

  Fly   153 TRELAYQIFETLKKVGKHH----DFSAGLIIGGKNLKFERTRMDQ-CNILICTPGRLLQHMDENP 212
            |||||.||...::..|  |    :.....|.||.:...:...:|: ..::|.|||||:..: ||.
  Fly   319 TRELAQQIQSVVRDYG--HLCKPEIRHTCIFGGSSKVPQARDLDRGVEVIIATPGRLIDFL-ENR 380

  Fly   213 LFNTSTMEMLVLDEADRCLDMGFQKTLNSIIENFPPVRQTLLFSATQTNTVQDLARLNLKDPVYV 277
            ..|......||||||||.|||||:..:..|||...|.||.:::|||....||.||...|.|.:.:
  Fly   381 NTNLQRCTYLVLDEADRMLDMGFEPQIRKIIEQIRPDRQVVMWSATWPKEVQALAGDFLNDYIQI 445

  Fly   278 GYGGATPREEPSASTKKTPNTAVLAVPEL---LQQSYVVLNLEDKITMLWSFIKN--HLKQKIIV 337
            ..|          |...:.|..:..:.|:   :::...::.|.::|    |.|||  :...||||
  Fly   446 NIG----------SMNLSANHNIRQIVEICTEIEKPQRLVCLLNEI----SPIKNSGNNGNKIIV 496

  Fly   338 FVASCKQAKYLYEIFCKLRPGSPLLALYGTLHQDRRIAIYEDFLRKSHVVMFSTDVASRGLDFPA 402
            ||.:..:.:.:.:|.  ...|....:::|...|:.|.::.:||......::.:|||||||||...
  Fly   497 FVETKIKVEDILQII--RAEGYNATSIHGDKTQNERDSVLKDFRNGKSNILIATDVASRGLDVED 559

  Fly   403 VNWVVQLDCPEDVSQYIHRAGRSARNKTRGECLLVLTP---SEEEYMISALKE 452
            :.:|:..|.|.....|:||.||:.|.:..|......||   .:...:||.|:|
  Fly   560 LQYVINYDYPNSSENYVHRIGRTGRCQQLGTAYTFFTPDNAKQARELISVLEE 612

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5800	NP_573230.1	PRK01297	2..471	CDD:234938	143/508 (28%)
		DEADc	74..277	CDD:238167	76/208 (37%)
		HELICc	311..437	CDD:238034	38/127 (30%)
		DUF4217	474..530	CDD:290667
mahe	NP_001284994.1	PTZ00110	136..656	CDD:240273	140/501 (28%)
		DEADc	239..446	CDD:238167	76/209 (36%)
		HELICc	457..594	CDD:238034	39/142 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451442
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840