Protein Alignment CG5800 and ddx27

DIOPT Version :10

• Sequence 1: NP_573230.1
• Gene: CG5800 / 32742
• FlyBaseID: FBgn0030855
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_593214.2
• Gene: ddx27 / 2543155
• PomBaseID: SPAC30D11.03
• Length: 714
• Species: Schizosaccharomyces pombe
• Alignment Length: 658
• Identity: 183/658 - (27%)
• Similarity: 281/658 - (42%)
• Gaps: 149/658 - (22%)

  Fly    32 SGDNSQKRPRQEINKSRLAATEAEIQDLKTKYAEIDATAIKKFAQFPLSKKTQKALAESKFVHPT 96
            :|.:..:...:||.|......|.:      |...:..|....|....||:...|.|:...|..||
pombe   185 AGSSDSEEDEEEIAKKNAFFAEGD------KEKSMMTTTHSSFQSMNLSRPILKGLSNLGFEVPT 243

  Fly    97 QVQRDSIGPALQGKDVLGAAITGSGKTLAFLIPVLEHLFMNKWSRTDGVGAIIISPTRELAYQIF 161
            |:|..:|..||.|||::|||:||||||.||::|:||.| :.:..:......:|:.||||||.|..
pombe   244 QIQDKTIPLALLGKDIVGAAVTGSGKTAAFIVPILERL-LYRPKKVPTTRVLILCPTRELAMQCH 307

  Fly   162 ETLKKVGKHHDFSAGLIIGGKNLKFE----RTRMDQCNILICTPGRLLQHMDENPLFNTSTMEML 222
            ....|:....|....|.|||.:||.:    |.|.|   |:|.||||.:.||..:..|....:|::
pombe   308 SVATKIASFTDIMVCLCIGGLSLKLQEQELRKRPD---IVIATPGRFIDHMRNSQGFTVENIEIM 369

  Fly   223 VLDEADRCLDMGFQKTLNSIIENFPPVRQTLLFSATQTNTVQDLARLNLKDPVYVGYGGATPREE 287
            |:|||||.|:.||...||.||:..|..|||:|||||.|:.|.||.||:|..||.|
pombe   370 VMDEADRMLEDGFADELNEIIQACPKSRQTMLFSATMTDKVDDLIRLSLNRPVRV---------- 424

  Fly   288 PSASTKKTPNTAVLAVPELLQQSYVVLNLEDKI---TMLWSFIKNHLKQKIIVFVASCKQAKYLY 349
             ....|||  ||     :||.|.:|.:..:.::   .||....|....::.|:|..|...|..:.
pombe   425 -FVDNKKT--TA-----KLLTQEFVRVRPQRELLRPAMLIYLCKELFHRRTIIFFRSKAFAHKMR 481

  Fly   350 EIFCKLRPGSPLLAL-----YGTLHQDRRIAIYEDFLRKSHVVMFSTDVASRGLDFPAVNWVVQL 409
            .||       .||:|     :|:|.|::|:...|||.......:.:|||||||:|...:..|:..
pombe   482 VIF-------GLLSLNATEIHGSLSQEQRVRALEDFRDGKCNYLLATDVASRGIDIKGIEVVINY 539

  Fly   410 DCPEDVSQYIHRAGRSARNKTRGECLLVLTPSEEEYMISALKEQLNIDIRCVQIDPKKLFSPRVK 474
            :.|.....|:||.||:||....|..:.:....:.:.:....|
pombe   540 EAPATHEVYLHRVGRTARAGRSGRAITLAGEGDRKVLKGVFK----------------------- 581

  Fly   475 IEAFLAQFPELRATAQRAFLSYIKSVFLMRNKRLFNVFSLDLDAFAQSLGLAVTPRVPFLEKFLW 539
                       .::||              |.:|.| .:||.:.               :|||
pombe   582 -----------NSSAQ--------------NTKLVN-RNLDFNK---------------VEKF-- 603

  Fly   540 RQKQLQQQKEQGDNAKSINPLLSKLTKQQSFGGGDEDEENSDDEDFIKVKRKDHDVEGEPVKLDE 604
                       |...:.:.|::.|:.          |||..:.|  :|:..:|.. :||.: :..
pombe   604 -----------GKEIEELEPVVQKVL----------DEEKQERE--LKIAERDLK-KGENI-MKY 643

  Fly   605 EDDTENEAEAPLVVPKREKLVTKASLAKKALKKNLQVNSKLKFDDE---------GETMADDRSQ 660
            .|:..:.........:::|..:|||.||.  ||:|....|....:|         .:.:::.:|.
pombe   644 GDEIRSRPARTWFQSEKDKQASKASEAKD--KKSLAKRKKQMEKEEVPRAYKKTKNDRLSNKKST 706

  Fly   661 MKALSARQ 668
            .|:.|.|:
pombe   707 KKSKSKRK 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5800	NP_573230.1	SrmB	71..493	CDD:440279	141/433 (33%)
		DEADc_DDX10	83..279	CDD:350699	89/199 (45%)
		DUF4217	474..530	CDD:464056	7/55 (13%)
ddx27	NP_593214.2	SrmB	220..655	CDD:440279	161/554 (29%)