Protein Alignment CG8289 and CBX8

DIOPT Version :10

• Sequence 1: NP_573229.1
• Gene: CG8289 / 32741
• FlyBaseID: FBgn0030854
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_065700.1
• Gene: CBX8 / 57332
• HGNCID: 15962
• Length: 389
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 66/313 - (21%)
• Similarity: 110/313 - (35%)
• Gaps: 83/313 - (26%)

  Fly    35 GRSSRKTPNKRKAKLTV----ASDSEDSDCQTSTSNVDVPAARNK-RKVGKARNATTSPRKNGKK 94
            |||.:...:..:|:..:    .|....|...:||...:.|..|:: |...:.|:......:..::
Human   108 GRSPQDLASTSRAREGLRNMGLSPPASSTSTSSTCRAEAPRDRDRDRDRDRERDRERERERERER 172

  Fly    95 IVIEDSDDDANHSDVDPSA--DSSPR---KPNIKRQTRRSVRGETEDSNELPSTSKASAHASSPI 154
            ....:.:...:..|..||:  |||.:   ||          |.|..|.::.| ..:.||.....:
Human   173 ERERERERGTSRVDDKPSSPGDSSKKRGPKP----------RKELPDPSQRP-LGEPSAGLGEYL 226

  Fly   155 KKRKLSRASTSSVK--NGKKVAE--KDSESD-VDAGTEDEKSAQ----------PQKVAAKSKSS 204
            |.|||....:.:.|  .|..|.:  :..:|| |..|.....||:          |.:|.   |..
Human   227 KGRKLDDTPSGAGKFPAGHSVIQLARRQDSDLVQCGVTSPSSAEATGKLAVDTFPARVI---KHR 288

  Fly   205 PNAKKAKGRGRRNA-GTKKADDSIDPEK-------------------QWEVEKILDHVATKEGDM 249
            ....:|||:|..:. ||:....|..|..                   :..|.:||       ||
Human   289 AAFLEAKGQGALDPNGTRVRHGSGPPSSGGGLYRDMGAQGGRPSLIARIPVARIL-------GD- 345

  Fly   250 FKIRWKKYGPKDDSWEPS----KNLACDALIEKFMRKQATQENVD---VKELR 295
                     |:::||.||    :.:....:...|:.....:.|.|   .||.|
Human   346 ---------PEEESWSPSLTNLEKVVVTDVTSNFLTVTIKESNTDQGFFKEKR 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8289	NP_573229.1	CD_CSD	233..281	CDD:349274	11/51 (22%)
CBX8	NP_065700.1	CD_polycomb_like	11..59	CDD:349277
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..241		26/127 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..327		5/28 (18%)
		CBX7_C	349..381	CDD:465385	6/31 (19%)