DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8289 and Cbx8

DIOPT Version :9

Sequence 1:	NP_573229.1	Gene:	CG8289 / 32741	FlyBaseID:	FBgn0030854	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_038954.1	Gene:	Cbx8 / 30951	MGIID:	1353589	Length:	362	Species:	Mus musculus

Alignment Length:	300	Identity:	73/300 - (24%)
Similarity:	103/300 - (34%)	Gaps:	84/300 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 GRS-------SRKTPNKRKAKLTVASDSEDSDCQTSTSNVDVPAARNKRKVGKARNATTSPRKNG 92
            |||       ||.....|...|.....|      |||...|.|..|::.            |..|
Mouse   108 GRSPQDLASTSRAREGLRNTGLPPPGSS------TSTCRADPPRDRDRE------------RDRG 154

  Fly    93 KKIVIEDSDDDANHSDVDPSADSSPRKPNIKRQTRRSVRGETEDSNELPSTSKASAHASSPIKKR 157
            ...|     ||...|..|.|....| ||          |.|..|.::.| ..:.||.....:|.|
Mouse   155 TSRV-----DDKPSSPGDSSKKRGP-KP----------RKEPLDPSQRP-LGEPSAGLGEYLKGR 202

  Fly   158 KLSRASTSSVK--NGKKVAE--KDSESD-VDAGTEDEKSAQ-PQKVAAKS------KSSPNAKKA 210
            ||...|:.:.|  .|..|.:  :..:|| |..|.....||: ..|:|..:      |......:|
Mouse   203 KLDETSSGTGKFPAGHSVIQLARRQDSDLVQYGVTSPSSAEASSKLAVDTFPARVIKHRAAFLEA 267

  Fly   211 KGRG---------RRNAGTKKADDSI--DPEKQWEVEKILDH--VATKEGDMFKIRWKKYGPKDD 262
            ||:|         |.::||..:..|:  |...|.....::..  ||...||          |:::
Mouse   268 KGQGALDPGGARVRHSSGTPASVGSLYRDMGAQGGRPSLIARIPVARILGD----------PEEE 322

  Fly   263 SWEPS----KNLACDALIEKFMRKQATQENVD---VKELR 295
            ||.||    :.:....:...|:.....:.|.|   .||.|
Mouse   323 SWSPSLTNLEKVVVTDVTSNFLTVTIKESNTDQGFFKEKR 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8289	NP_573229.1	CHROMO	233..284	CDD:214605	10/56 (18%)
Cbx8	NP_038954.1	CHROMO	10..62	CDD:214605
Cbx8	NP_038954.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	90..197		31/123 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920