DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8289 and Mphosph8

DIOPT Version :9

Sequence 1:	NP_573229.1	Gene:	CG8289 / 32741	FlyBaseID:	FBgn0030854	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_001017375.2	Gene:	Mphosph8 / 290270	RGDID:	1305133	Length:	851	Species:	Rattus norvegicus

Alignment Length:	180	Identity:	53/180 - (29%)
Similarity:	80/180 - (44%)	Gaps:	47/180 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 AGTEDEKSAQPQKVAAKSKSSPN----AKKAKGRG----RRNAGTK----KADDSIDPEKQWEVE 236
            |.||:..|     |||...|.|:    :.:.:|.|    .::|.||    ..|...|.|..:|||
  Rat     3 AATEENMS-----VAALVMSVPDNIGRSPEVEGGGAAGEEKDAATKGTVAVGDSEEDGEDVFEVE 62

  Fly   237 KILDHVATKEGDMFKIRWKKYGPKDDSWEPSKNLA-CDALIEKFMRKQATQENVDVKELRESPKK 300
            :|||.......:::|:|||.|...||:|||..:|. |..::.:|.:|.|  || ..|.:|:..:|
  Rat    63 RILDMKCEGGKNLYKVRWKGYTSDDDTWEPEVHLEDCKEVLLEFRKKVA--EN-KAKAVRKDIQK 124

  Fly   301 TERLVDECYPRTNLHNRI--------------ERSSKRSSAKNRIFYGEE 336
                       .:|:|.|              |.:|.|.. |.:|.|.|:
  Rat   125 -----------LSLNNDIFEADSDIDQQGDTKEDTSPRKK-KKKIKYKED 162

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8289	NP_573229.1	CHROMO	233..284	CDD:214605	20/51 (39%)
Mphosph8	NP_001017375.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	21..54		6/32 (19%)
		CHROMO	58..109	CDD:214605	19/50 (38%)
		Histone H3K9me3 binding. /evidence=ECO:0000250\|UniProtKB:Q99549	80..87		3/6 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	133..174		7/31 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	240..302
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	315..428
		ANK	586..710	CDD:238125
		ANK 1	591..620
		ANK repeat	594..622	CDD:293786
		Ank_2	597..686	CDD:289560
		ANK repeat	624..655	CDD:293786
		ANK 2	624..653
		ANK repeat	657..686	CDD:293786
		ANK 3	657..686
		ANK 4	690..719
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820