DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8289 and Cdyl

DIOPT Version :9

Sequence 1:	NP_573229.1	Gene:	CG8289 / 32741	FlyBaseID:	FBgn0030854	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_034011.1	Gene:	Cdyl / 12593	MGIID:	1339956	Length:	593	Species:	Mus musculus

Alignment Length:	152	Identity:	33/152 - (21%)
Similarity:	65/152 - (42%)	Gaps:	30/152 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 SESDVDAGTEDEKSAQPQKVAAKSKSSPNAKKAKGRGRRNAGTKKADDSIDPEKQWEVEKILDHV 242
            :|...|..|..:.:..|..|:...::||..:.|                     :.:||.|:|..
Mouse    22 AEQPTDDNTCQQNNVVPATVSEPDQASPAIQDA---------------------ETQVESIVDKR 65

  Fly   243 ATKEGDM-FKIRWKKYGPKDDSWEPSKNLA-CDALIEKFMRK--QATQENVDVKELRESPKKTER 303
            ..|:|.. :.:|||.|..:||:|||.::|. |:..|..|.|:  :..:|....:..|.||....:
Mouse    66 KNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHNERQKEGSLARASRASPSNARK 130

  Fly   304 LVDECYPRTNLHNRIERSSKRS 325
            .:..     :.|:.:.:::.::
Mouse   131 QISR-----STHSTLSKTNSKA 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8289	NP_573229.1	CHROMO	233..284	CDD:214605	20/54 (37%)
Cdyl	NP_034011.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..30		2/7 (29%)
		CHROMO	55..109	CDD:214605	20/53 (38%)
		Interaction with EZH2. /evidence=ECO:0000250\|UniProtKB:Q9Y232	56..304		25/97 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	110..158		5/43 (12%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	200..223
		crotonase-like	339..535	CDD:119339
		Acetyl-CoA-binding domain. /evidence=ECO:0000255	357..589
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810