DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8289 and Cbx5

DIOPT Version :9

Sequence 1:	NP_573229.1	Gene:	CG8289 / 32741	FlyBaseID:	FBgn0030854	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_001070257.1	Gene:	Cbx5 / 12419	MGIID:	109372	Length:	191	Species:	Mus musculus

Alignment Length:	131	Identity:	37/131 - (28%)
Similarity:	64/131 - (48%)	Gaps:	17/131 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   208 KKAKGRGRRNAGTKKADDSIDPEKQWEVEKILDHVATKEGDMFKIRWKKYGPKDDSWEPSKNLAC 272
            ||.|    |.|.:..::|    |:::.|||:||....|....:.::||.:..:.::|||.|||.|
Mouse     3 KKTK----RTADSSSSED----EEEYVVEKVLDRRMVKGQVEYLLKWKGFSEEHNTWEPEKNLDC 59

  Fly   273 DALIEKFMRKQATQENVDVKELRESPKKTERLVDECYPRTNLHNRIE--RSSKRSSAKNRIFYGE 335
            ..||.:||:|....:..:..:.||..:..:|       :::..|..:  :|.|:....|.|..|.
Mouse    60 PELISEFMKKYKKMKEGENNKPREKSEGNKR-------KSSFSNSADDIKSKKKREQSNDIARGF 117

  Fly   336 E 336
            |
Mouse   118 E 118

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8289	NP_573229.1	CHROMO	233..284	CDD:214605	20/50 (40%)
Cbx5	NP_001070257.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21		7/25 (28%)
		CD_HP1alpha_Cbx5	19..68	CDD:349298	18/48 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	70..117		8/53 (15%)
		CSD_HP1alpha_Cbx5	116..173	CDD:349302	2/3 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1911
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1628171at2759
OrthoFinder	1	1.000	-	-		FOG0000191
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820