DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ND-24 and Ndufv2

DIOPT Version :9

Sequence 1:	NP_001285378.1	Gene:	ND-24 / 32740	FlyBaseID:	FBgn0030853	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	NP_112326.1	Gene:	Ndufv2 / 81728	RGDID:	621733	Length:	248	Species:	Rattus norvegicus

Alignment Length:	244	Identity:	156/244 - (63%)
Similarity:	190/244 - (77%)	Gaps:	13/244 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 AVRANIRAIATSSARASDN-------------LFVHRDTPEDNPNIPFEFTAENKKRVEAILSIY 63
            |:||....:.....|.:.|             |||||||||:||:.||:||.||.:|:|||:..|
  Rat     5 ALRARASGLTAQWGRHARNLHKTAVQNGAGGALFVHRDTPENNPDTPFDFTPENYERIEAIVRNY 69

  Fly    64 PEGHKRGAMIPLLDLAQRQYGWLPISAMHKVAEILQLPNMRVYEVATFYTMFMRKPTGKYHIQVC 128
            ||||:..|::|:|||||||.||||||||:||||:||:|.||||||||||||:.|||.||||||||
  Rat    70 PEGHRAAAVLPVLDLAQRQNGWLPISAMNKVAEVLQVPPMRVYEVATFYTMYNRKPVGKYHIQVC 134

  Fly   129 TTTPCWLRGSDDILETCKKQLGIGVGDTTKDRKFTISEVECLGACVNAPMVAINDDYYEDLTSKD 193
            |||||.||.||.||||.:::|||.||:||.|:.||:.||||||||||||||.||||||||||.||
  Rat   135 TTTPCMLRDSDSILETLQRKLGIKVGETTPDKLFTLIEVECLGACVNAPMVQINDDYYEDLTPKD 199

  Fly   194 MQDILNDLKADKISPPGPRNGRFASEPKGEPTSLSEEPKGPGFGLQAGL 242
            :::|:::|:|.|:..||||:|||..||.|..|||:|.|||||||:||||
  Rat   200 IEEIIDELRAGKVPKPGPRSGRFCCEPAGGLTSLTEPPKGPGFGVQAGL 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ND-24	NP_001285378.1	2Fe-2S_thioredx	56..202	CDD:396008	105/145 (72%)
Ndufv2	NP_112326.1	NuoE	50..211	CDD:224817	114/160 (71%)
		2Fe-2S_thioredx	62..208	CDD:279582	105/145 (72%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	229..248		13/18 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340850
Domainoid	1	1.000	227	1.000	Domainoid score	I2426
eggNOG	1	0.900	-	-		E1_COG1905
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10884
Inparanoid	1	1.050	324	1.000	Inparanoid score	I2404
OMA	1	1.010	-	-		QHG54082
OrthoDB	1	1.010	-	-		D1396088at2759
OrthoFinder	1	1.000	-	-		FOG0004458
OrthoInspector	1	1.000	-	-		oto97346
orthoMCL	1	0.900	-	-		OOG6_101311
Panther	1	1.100	-	-	LDO	PTHR10371
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3749
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770