DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ND-24 and ndufv2

DIOPT Version :9

Sequence 1:	NP_001285378.1	Gene:	ND-24 / 32740	FlyBaseID:	FBgn0030853	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	NP_957041.1	Gene:	ndufv2 / 393720	ZFINID:	ZDB-GENE-040426-1713	Length:	244	Species:	Danio rerio

Alignment Length:	242	Identity:	151/242 - (62%)
Similarity:	190/242 - (78%)	Gaps:	1/242 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LTNCASKTLAAVRANIRAIATSSARA-SDNLFVHRDTPEDNPNIPFEFTAENKKRVEAILSIYPE 65
            |::.....::.....:|::..:|||| :..:||||||||:||:.|||||.||.||||||::.|||
Zfish     3 LSSTLRSAVSYTARQVRSLHQTSARAGAGGIFVHRDTPENNPDTPFEFTPENMKRVEAIINNYPE 67

  Fly    66 GHKRGAMIPLLDLAQRQYGWLPISAMHKVAEILQLPNMRVYEVATFYTMFMRKPTGKYHIQVCTT 130
            |||..|.||:|||||||.||||||||:||||:|.:..|||||||||||||:|:|.||||||:|||
Zfish    68 GHKAAATIPVLDLAQRQNGWLPISAMNKVAEVLGIAPMRVYEVATFYTMFLRQPVGKYHIQICTT 132

  Fly   131 TPCWLRGSDDILETCKKQLGIGVGDTTKDRKFTISEVECLGACVNAPMVAINDDYYEDLTSKDMQ 195
            |||.|..||.|||..:.:|||.||:||.|:.||::||||||||||||||.|||:|||||...||:
Zfish   133 TPCMLCDSDSILEAIQNKLGIKVGETTADKLFTLTEVECLGACVNAPMVQINDNYYEDLKPSDME 197

  Fly   196 DILNDLKADKISPPGPRNGRFASEPKGEPTSLSEEPKGPGFGLQAGL 242
            .|:::|||.::.|||||:|||:.||.|..|||:|.|.|||.|::|.|
Zfish   198 QIIDELKAGRVPPPGPRSGRFSCEPAGGLTSLTEPPPGPGVGVRADL 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ND-24	NP_001285378.1	2Fe-2S_thioredx	56..202	CDD:396008	101/145 (70%)
ndufv2	NP_957041.1	NuoE	46..206	CDD:224817	112/159 (70%)
ndufv2	NP_957041.1	2Fe-2S_thioredx	58..204	CDD:279582	101/145 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580698
Domainoid	1	1.000	217	1.000	Domainoid score	I2637
eggNOG	1	0.900	-	-		E1_COG1905
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10884
Inparanoid	1	1.050	314	1.000	Inparanoid score	I2544
OMA	1	1.010	-	-		QHG54082
OrthoDB	1	1.010	-	-		D1396088at2759
OrthoFinder	1	1.000	-	-		FOG0004458
OrthoInspector	1	1.000	-	-		oto41171
orthoMCL	1	0.900	-	-		OOG6_101311
Panther	1	1.100	-	-	LDO	PTHR10371
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R804
SonicParanoid	1	1.000	-	-		X3749
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800