DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ND-24 and F53F4.10

DIOPT Version :9

Sequence 1:	NP_001285378.1	Gene:	ND-24 / 32740	FlyBaseID:	FBgn0030853	Length:	242	Species:	Drosophila melanogaster
Sequence 2:	NP_506376.1	Gene:	F53F4.10 / 179850	WormBaseID:	WBGene00009992	Length:	239	Species:	Caenorhabditis elegans

Alignment Length:	212	Identity:	145/212 - (68%)
Similarity:	177/212 - (83%)	Gaps:	0/212 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LFVHRDTPEDNPNIPFEFTAENKKRVEAILSIYPEGHKRGAMIPLLDLAQRQYGWLPISAMHKVA 95
            |.|||||.|:|.|:.|:||:||::|::||:.|||||||.||:||||||||||:|||||||||:||
Worm    27 LMVHRDTKENNLNVKFKFTSENQERIKAIMDIYPEGHKAGALIPLLDLAQRQHGWLPISAMHEVA 91

  Fly    96 EILQLPNMRVYEVATFYTMFMRKPTGKYHIQVCTTTPCWLRGSDDILETCKKQLGIGVGDTTKDR 160
            :||::|.||.||||||||||.|:|.|||.:|||.||||.|||::.|.||.:|:|||..|:||||.
Worm    92 KILEVPRMRAYEVATFYTMFNRQPVGKYFLQVCATTPCMLRGAETITETIEKKLGIHAGETTKDG 156

  Fly   161 KFTISEVECLGACVNAPMVAINDDYYEDLTSKDMQDILNDLKADKISPPGPRNGRFASEPKGEPT 225
            .||::|||||||||||||:.|||||:||||.||:.:||:||||.:....|||:||.|:||.||.|
Worm   157 LFTLAEVECLGACVNAPMIQINDDYFEDLTPKDVNEILDDLKAGRKPAAGPRSGRLAAEPFGELT 221

  Fly   226 SLSEEPKGPGFGLQAGL 242
            ||.|.|.||||||||.|
Worm   222 SLKETPPGPGFGLQAAL 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ND-24	NP_001285378.1	2Fe-2S_thioredx	56..202	CDD:396008	103/145 (71%)
F53F4.10	NP_506376.1	NuoE	42..200	CDD:224817	111/157 (71%)
F53F4.10	NP_506376.1	2Fe-2S_thioredx	52..198	CDD:279582	103/145 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159348
Domainoid	1	1.000	229	1.000	Domainoid score	I1402
eggNOG	1	0.900	-	-		E1_COG1905
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10884
Inparanoid	1	1.050	310	1.000	Inparanoid score	I1557
Isobase	1	0.950	-	0	Normalized mean entropy	S1990
OMA	1	1.010	-	-		QHG54082
OrthoDB	1	1.010	-	-		D1396088at2759
OrthoFinder	1	1.000	-	-		FOG0004458
OrthoInspector	1	1.000	-	-		oto18833
orthoMCL	1	0.900	-	-		OOG6_101311
Panther	1	1.100	-	-	LDO	PTHR10371
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R804
SonicParanoid	1	1.000	-	-		X3749
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790