DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rrad and Rgk1

DIOPT Version :9

Sequence 1:	XP_021333082.1	Gene:	rrad / 327396	ZFINID:	ZDB-GENE-030131-5607	Length:	304	Species:	Danio rerio
Sequence 2:	NP_725875.3	Gene:	Rgk1 / 14462605	FlyBaseID:	FBgn0264753	Length:	1379	Species:	Drosophila melanogaster

Alignment Length:	354	Identity:	101/354 - (28%)
Similarity:	158/354 - (44%)	Gaps:	90/354 - (25%)

- Green bases have known domain annotations that are detailed below.

Zfish     7 LNKGDKLRNMDKRRGSMPFPLHLQTLHRRSMPVDDRELRSMPAAQPSELPGLMRFNADRNSCVSD 71
            :|:||.|::...|..:.....:..|.|     :..::..|.||:..:           |.|..|.
  Fly  1060 VNRGDSLKSRRSRSNNSVASSNSSTEH-----LTTQQQLSAPASVSA-----------RTSLASS 1108

Zfish    72 SSDSVISSGSDSDGQVYKVVLLGEHGVGKSSLARIFGGVE-----DSNDCEETGNTYDRSLVVDD 131
            ...|..:.|:..    |:|::||...||||||...|...|     |::..:|:|.. ..|:::..
  Fly  1109 RESSTSNPGNGP----YRVLMLGGPAVGKSSLVSQFMTSEYLHAYDTSIDDESGEK-AVSVLLSG 1168

Zfish   132 EETSILLYDIWEQDNSQWLQDQCMRMGD--AYIIVYSVTDKSSFEKASELRIQLRRARQSENI-- 192
            ||:.::..|   ...::...|:|:...|  .|.::||..|:|||..|.::   |:....::||
  Fly  1169 EESELIFID---HGYTEMTPDECLTNYDPHGYCVIYSAADRSSFSVAEQV---LQVLWTNQNIAQ 1227

Zfish   193 -PIILVGNKSDLVRSREVSMDEGSACAVVFDCKFIETSASLHHNVRDLFEGIVRQIRLRKDSKEE 256
             .:|||.||:||.|||.|:.:||.|.|..:||||||||..::|||.:|..|::.||||:.::.|:
  Fly  1228 KAVILVSNKADLARSRLVTSEEGKAMATAYDCKFIETSVGINHNVDELLVGLLSQIRLKLENPEK 1292

Zfish   257 N-----ARRMANCKR-----------------------------------------RESISKKAK 275
            :     .|.:...||                                         |.|.|.|.|
  Fly  1293 SRDLFRKRSIRKSKRRACSPLNAGCLNANTPLGPLGEAVATPPGSAQSSPRKYRGSRTSTSLKVK 1357

Zfish   276 RFLGRMVARKNKKMAFRQKSKSCHDLSVL 304
            ..|||:..|.:       |||||.:|.||
  Fly  1358 GLLGRVWTRDS-------KSKSCENLHVL 1379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rrad	XP_021333082.1	RGK	88..304	CDD:206715	84/271 (31%)
Rgk1	NP_725875.3	DUF2967	459..715	CDD:288079
		P-loop_NTPase	1121..1379	CDD:304359	84/271 (31%)
		small_GTPase	1121..1286	CDD:197466	64/171 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D301527at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_109169
Panther	1	1.100	-	-	O	PTHR45775
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5084
SonicParanoid	1	1.000	-	-		X743
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.950