DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stas and tmem41b

DIOPT Version :9

Sequence 1:	NP_573225.1	Gene:	stas / 32737	FlyBaseID:	FBgn0030850	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_001073456.1	Gene:	tmem41b / 561208	ZFINID:	ZDB-GENE-061215-138	Length:	282	Species:	Danio rerio

Alignment Length:	265	Identity:	126/265 - (47%)
Similarity:	181/265 - (68%)	Gaps:	0/265 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 QQQQQQQQATPQKQAMSADEKKATKKSLVIVAGIFVASLVTMCYVYAIFPELNASEKQHLKIPRD 119
            :|:.:..:.||..:...:....:.:.|::::..||..|...|..|:..||:|:..|::.:|||:|
Zfish    18 EQEPRPSKETPVPKGAQSPGGASARMSILLLVVIFACSACVMYLVFRNFPQLSEDEREKIKIPKD 82

  Fly   120 IQDAKMLAKVLDRYKDMYYFEVMFGVVVAYVFLQTFAIPGSLFLSILLGFLYKFPIALFLICFCS 184
            ::|||.|..||.:|||.||.:|:......|:||||||||||:|||||.|:||.||:||||:|.||
Zfish    83 MEDAKALGTVLSKYKDTYYTQVLLAYFATYIFLQTFAIPGSIFLSILSGYLYPFPLALFLVCLCS 147

  Fly   185 ALGATLCYTLSNLVGRRLIRHFWPKKTSEWSKHVEEYRDSLFNYMLFLRMTPILPNWFINLASPV 249
            .|||:.||.||.||||.::..:..::..:||:.|:::|:.|.||::|||:||.|||||||:.|||
Zfish   148 GLGASFCYMLSYLVGRPMVYKYLTERAQKWSQQVDKHREHLINYIIFLRITPFLPNWFINITSPV 212

  Fly   250 IGVPLHIFALGTFCGVAPPSVIAIQAGKTLQKMTSSSEAFSWTSMGILMACACASLLPGLLKNKF 314
            |.|||.:|.||||.||||||.:||.||.||.|:|::.||.||.|:.:|...|..|:||...:.|.
Zfish   213 INVPLGVFFLGTFLGVAPPSFVAINAGTTLYKLTTAGEAVSWNSLLVLGVLAVVSILPVCFQKKL 277

  Fly   315 KHKKE 319
            :.|.|
Zfish   278 QQKLE 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stas	NP_573225.1	SNARE_assoc	157..276	CDD:286425	71/118 (60%)
tmem41b	NP_001073456.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..36		3/17 (18%)
		SNARE_assoc	120..239	CDD:286425	71/118 (60%)
		VTT domain, required for its function in autophagy. /evidence=ECO:0000250\|UniProtKB:Q5BJD5	131..242		64/110 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588175
Domainoid	1	1.000	165	1.000	Domainoid score	I3877
eggNOG	1	0.900	-	-		E1_COG0398
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H42740
Inparanoid	1	1.050	271	1.000	Inparanoid score	I2977
OMA	1	1.010	-	-		QHG54676
OrthoDB	1	1.010	-	-		D1222755at2759
OrthoFinder	1	1.000	-	-		FOG0001464
OrthoInspector	1	1.000	-	-		oto39258
orthoMCL	1	0.900	-	-		OOG6_102890
Panther	1	1.100	-	-	LDO	PTHR43220
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2849
SonicParanoid	1	1.000	-	-		X2798
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800