DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stas and tmem41b

DIOPT Version :9

Sequence 1:	NP_573225.1	Gene:	stas / 32737	FlyBaseID:	FBgn0030850	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_001016955.1	Gene:	tmem41b / 549709	XenbaseID:	XB-GENE-978007	Length:	278	Species:	Xenopus tropicalis

Alignment Length:	264	Identity:	137/264 - (51%)
Similarity:	178/264 - (67%)	Gaps:	12/264 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 QAMSADEKKA------------TKKSLVIVAGIFVASLVTMCYVYAIFPELNASEKQHLKIPRDI 120
            |.....||||            .:.||:|:..||:.:...|..||..||:|:..|::.:|:|||:
Frog    15 QCNHGSEKKAPATGKVHSEGGSARMSLLILVSIFLCAASIMFLVYKHFPQLSEEEREKIKVPRDM 79

  Fly   121 QDAKMLAKVLDRYKDMYYFEVMFGVVVAYVFLQTFAIPGSLFLSILLGFLYKFPIALFLICFCSA 185
            .|||.|.|||.:|||.:|.||:......|:||||||||||:|||||.||||.||:||||:|.||.
Frog    80 DDAKALGKVLSKYKDTFYVEVLVAYFTTYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSG 144

  Fly   186 LGATLCYTLSNLVGRRLIRHFWPKKTSEWSKHVEEYRDSLFNYMLFLRMTPILPNWFINLASPVI 250
            |||:.||.||.||||.::..:...|..:||:.||.:||.|.||::|||:||.|||||||:.||||
Frog   145 LGASFCYLLSYLVGRPVVYKYLSDKAIKWSQQVERHRDHLINYIIFLRITPFLPNWFINITSPVI 209

  Fly   251 GVPLHIFALGTFCGVAPPSVIAIQAGKTLQKMTSSSEAFSWTSMGILMACACASLLPGLLKNKFK 315
            .|||.:|.||||.||||||.:||:||.||.::|::.||.||.|:.|||..|..|:||.:.:.|.|
Frog   210 NVPLKVFFLGTFIGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSVIILMVLAVLSILPAIFQKKLK 274

  Fly   316 HKKE 319
            .|.|
Frog   275 KKFE 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stas	NP_573225.1	SNARE_assoc	157..276	CDD:286425	75/118 (64%)
tmem41b	NP_001016955.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31		5/15 (33%)
		VTT	116..235	CDD:378149	75/118 (64%)
		VTT domain, required for its function in autophagy. /evidence=ECO:0000250\|UniProtKB:Q5BJD5	127..238		68/110 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	168	1.000	Domainoid score	I3781
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H42740
Inparanoid	1	1.050	279	1.000	Inparanoid score	I2847
OMA	1	1.010	-	-		QHG54676
OrthoDB	1	1.010	-	-		D1222755at2759
OrthoFinder	1	1.000	-	-		FOG0001464
OrthoInspector	1	1.000	-	-		otm48366
Panther	1	1.100	-	-	LDO	PTHR43220
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2849
SonicParanoid	1	1.000	-	-		X2798
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110