DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment stas and egli-1

DIOPT Version :9

Sequence 1:	NP_573225.1	Gene:	stas / 32737	FlyBaseID:	FBgn0030850	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_495985.1	Gene:	egli-1 / 183942	WormBaseID:	WBGene00006520	Length:	246	Species:	Caenorhabditis elegans

Alignment Length:	245	Identity:	123/245 - (50%)
Similarity:	175/245 - (71%)	Gaps:	5/245 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 EKKATKKS---LVIVAGIFVASLVTMCYVYAIFPELNASEKQHLKIPRDIQDAKMLAKVLDRYKD 135
            |.|:::.|   ||::  ||....|::..||:.|||::|.||.|||.||:::|||.|.:||.:||:
Worm     2 ETKSSQTSHPWLVLL--IFATFAVSIFAVYSNFPEVSADEKVHLKYPRNLEDAKQLGRVLSKYKE 64

  Fly   136 MYYFEVMFGVVVAYVFLQTFAIPGSLFLSILLGFLYKFPIALFLICFCSALGATLCYTLSNLVGR 200
            ..|..|:.||:|.|||||:||||||:||:||.|:|:.|.:|:.|:|.|||.||.:|||:|.|.||
Worm    65 NNYSVVLCGVIVVYVFLQSFAIPGSIFLTILSGYLFPFYVAIVLVCSCSATGAAICYTISKLFGR 129

  Fly   201 RLIRHFWPKKTSEWSKHVEEYRDSLFNYMLFLRMTPILPNWFINLASPVIGVPLHIFALGTFCGV 265
            ..:...:|::.::|...:.::||...|||:|||:|||:|||.||:||||:.|||..|..|||.||
Worm   130 SFVLQKFPERIAKWQDDLSKHRDDFLNYMIFLRVTPIVPNWLINIASPVLDVPLAPFFWGTFLGV 194

  Fly   266 APPSVIAIQAGKTLQKMTSSSEAFSWTSMGILMACACASLLPGLLKNKFK 315
            ||||.:.||||.||::::.:|.|:||:|:.:|...|..||.|.|||.|.|
Worm   195 APPSFLYIQAGSTLEQLSHTSVAWSWSSIVLLTGSAILSLAPILLKKKLK 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stas	NP_573225.1	SNARE_assoc	157..276	CDD:286425	63/118 (53%)
egli-1	NP_495985.1	SNARE_assoc	86..206	CDD:286425	64/119 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162780
Domainoid	1	1.000	147	1.000	Domainoid score	I2774
eggNOG	1	0.900	-	-		E1_COG0398
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H42740
Inparanoid	1	1.050	249	1.000	Inparanoid score	I2015
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54676
OrthoDB	1	1.010	-	-		D1222755at2759
OrthoFinder	1	1.000	-	-		FOG0001464
OrthoInspector	1	1.000	-	-		oto17898
orthoMCL	1	0.900	-	-		OOG6_102890
Panther	1	1.100	-	-	LDO	PTHR43220
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2849
SonicParanoid	1	1.000	-	-		X2798
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800