Protein Alignment Ankle2 and LOC4576014

DIOPT Version :10

• Sequence 1: NP_573221.2
• Gene: Ankle2 / 32732
• FlyBaseID: FBgn0028343
• Length: 1174
• Species: Drosophila melanogaster
• Sequence 2: XP_061502753.1
• Gene: LOC4576014 / 4576014
• VectorBaseID: AGAMI1_003595
• Length: 528
• Species: Anopheles gambiae
• Alignment Length: 500
• Identity: 130/500 - (26%)
• Similarity: 208/500 - (41%)
• Gaps: 125/500 - (25%)

  Fly   169 GFIIPLGSNSSMSNLLLSDSPTSSPSSSSNVIANGRQQQMQQQQQQQPQQPDVSGEGPPFRAPTK 233
            |.::|.....|:.|.|.  :||....:|..:..|.             .||.::...|   :|..
Mosquito    71 GQLLPFQDKPSLDNFLA--NPTDGYEASRGLTGNA-------------TQPVITHVTP---SPAL 117

  Fly   234 QELVEFRKQIEGGHIDRVKRIIWENPRFLISSGDTPTSLKEGCRYNAMHICAQVNKARIAQLLLK 298
            |:  .|.|.:..|.:.:|..::.:.|..||.|...|...... |.||:||.|:....::.:.:|.
Mosquito   118 QQ--RFIKAVGMGDLGQVSSLVRQVPGLLIDSTAHPRRFAAE-RLNALHIAARYGANQVGEFILA 179

  Fly   299 TISDREFTQLYVGKKGSGKMCAALNISLLDYYLNMPDKGRGETPLHFAAKNGHVAMVEVLVSYPE 363
            .::.....::|.|::.:....|.|.:.|||.|||..:....|||||.|||.|...||.:||:||:
Mosquito   180 MVASGAIAKVYAGRRSTIPDAAVLTVQLLDDYLNGAEMDAAETPLHLAAKYGWKPMVRILVAYPQ 244

  Fly   364 CKSLRNHEGKEPKEIIC-----LRNANATHVTIKKLELLLYDPHFVPVLRSQSNTLPPKVGQPFS 423
            |:..||..|:.|::::|     .||   ||...:.::.||.|.:|||::|::||...|.:|:||:
Mosquito   245 CEMKRNSSGQFPQDLVCESATPERN---THECRRAIDKLLRDSYFVPLIRTESNVELPYIGEPFA 306

  Fly   424 PKDPPNLQHKADDYEGLSVDLAISALAGPMSREKAMNFYRRWKTPPRVSNNVMSPLAGSPFSSPV 488
            .:..|:|.: ......|.....|:|.|||||..:|..|.|.|||||||
Mosquito   307 RRHLPDLGN-VGTIRKLRFLRIITAFAGPMSLSEAQAFRREWKTPPRV----------------- 353

  Fly   489 KVTPSKSIFDRSAGNSSPVHSGRRVLFSPLAEATSSPKPTKNVPNGTNECEHNNNNVKPVYPLEF 553
                   :...:||..:|               |||.:         ..||....    :|.
Mosquito   354 -------VVHANAGPGTP---------------TSSYQ---------YRCELTGR----LYD--- 380

  Fly   554 PATPIRKMKPDLFMAYRNNNSFDSPSLADDSQILDMSLSRSLNASLNDSFRERHIKNTDIEKGLE 618
                         .|:|:..:                           ...||..:...::..:|
Mosquito   381 -------------RAHRHQAA---------------------------GIGERAFRRAHVDCAME 405

  Fly   619 VVGRQLARQEQLEWREYWDFLDSFLDIGTTEGLARLEAYFLEKTE 663
            .:||.|||.:.:||:|||.||.::.::..|:.||..|.|...:.|
Mosquito   406 RIGRSLARTKGVEWKEYWAFLGAYQNLSDTQALAIFERYLERQVE 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ankle2	NP_573221.2	ANKYR	<243..386	CDD:440430	47/147 (32%)
		ANK repeat	280..335	CDD:293786	15/54 (28%)
		ANK repeat	337..369	CDD:293786	16/31 (52%)
LOC4576014	XP_061502753.1	None