Protein Alignment ppk23 and scnn1b

DIOPT Version :10

• Sequence 1: NP_001097011.1
• Gene: ppk23 / 32731
• FlyBaseID: FBgn0030844
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_001072437.1
• Gene: scnn1b / 779891
• XenbaseID: XB-GENE-949109
• Length: 646
• Species: Xenopus tropicalis
• Alignment Length: 667
• Identity: 123/667 - (18%)
• Similarity: 212/667 - (31%)
• Gaps: 238/667 - (35%)

  Fly     7 HPPESRTQRFLETLVIFRRSLI-------YQTKE----FFQNSTLHGVRYIAESGRPIGEKFMWF 60
            |....|.:|:      |.|:|.       |..||    |..|:..||.:.|.:.|..  ::.|||
 Frog     3 HVKMKRLKRY------FTRALHRIQKGPGYTYKELLVWFCDNTNTHGPKRIIKEGPK--KRVMWF 59

  Fly    61 CFTSIGA-----------VTALV--IIMSLWEKFQT-----------NP---------------- 85
            ..|.:.|           :|.|.  :.:||...|:|           ||
 Frog    60 ILTLVFAGLVFWQWGVLILTYLSYGVSVSLSIGFKTMEFPAVTVCNANPYKYSRVKPLLKDLDAL 124

  Fly    86 TITGLD--------------TDFHNQNVVFPTT-------VVCPEA---------AFDHDKTYEK 120
            ..|.||              ....||||....|       ||..|.         .||::..|.|
 Frog   125 VATALDRIQFSSQDQANTFTQSSTNQNVTLDPTLWNHIPLVVIDETDPSNPIVNNIFDNNAIYSK 189

  Fly   121 VYNTLANYDEAQ---AQMYTPFLRILTSLNFENVRDAKVLSQSIPQNLLDA-HTIREWAFEGHID 181
             .|:..|..|.|   :|.|...:::.|:.|          :|.:.:|.... ..::||..   :.
 Frog   190 -NNSFRNSSEDQTSYSQRYKVAMKLCTNNN----------TQCVYRNFTSGIQALQEWYL---LQ 240

  Fly   182 CKNVF--------VSCKYRDEDI---------PCC-DHFEPIY-TEHGFCYAFN-SRFKSTPTED 226
            ..::|        ::..::.||:         ||. .:|..|| .::|.||.|| .:....|...
 Frog   241 LSSIFSNVPLADRIAMGFKAEDLILTCLFGGQPCSYRNFTRIYDADYGNCYIFNWGQEGEDPMAS 305

  Fly   227 VKTGAPHDL---YETDKKWALFFIPNSTSRIFIFSNEEYFGSDFNAQIDWSEPQLVEVRI-SKKN 287
            ...||...|   .:.::...|.::..:.:...|...:..|            |.:.::.| :...
 Frog   306 ANPGADFGLKLVLDIEQGEYLPYVQTTAAARLILHQQRSF------------PFVKDLGIYAMPG 358

  Fly   288 TYTT-----DDARQLSIGQRKCIFSDE---VKLNY--FPDAYTFSSCMKQCRMNKAIKLCKCNPP 342
            |.|:     |....:......|..:..   |:..|  |..:|:..||::.|...:.::.|.|..
 Frog   359 TETSIAVLVDQLEHMEAPYSSCTVNGSDIPVQNLYAEFNSSYSIQSCLRSCYQEQMVQTCGCAD- 422

  Fly   343 FYKPIRELSCVINIFTNLIAYILLLYLTPKAN-VPMCSIKDF----DCLDEFKSNITNIKDCLQ- 401
                                     |..|..| ...||...:    .|....:.::.:.:.|:.
 Frog   423 -------------------------YQYPLPNGSEYCSNDKYPDWVPCYYGLRDSVADRESCISL 462

  Fly   402 CELSCSKTVFNIDKLIKMSDRPES-----------------------------LGVLVEFLTWPI 437
            |:..|:.|.:.:  :|.|:|.|.:                             |.:..:...:..
 Frog   463 CQQPCNDTQYKM--VISMADWPSAGAQDWIFHVLSYEKDSSHNITVNRNGIVRLNIYFQEFNYRS 525

  Fly   438 IRYKREVLFGWVDLLVSFGGIASLFLGFSLLSGVEI-------IYYFTLRACCMVYKNRQELYEI 495
            |.........|  ||.:.||....::|.|:|..:|.       ::...|:....:...||.
 Frog   526 ITESEATNVVW--LLSNLGGQFGFWMGGSVLCIIEFGEIIIDCVWITILKLLAWIKDRRQR---- 584

  Fly   496 EEKIRQ-----EPPPKI 507
                ||     :|||.:
 Frog   585 ----RQRAQYADPPPTV 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk23	NP_001097011.1	ASC	34..476	CDD:459966	106/591 (18%)
scnn1b	NP_001072437.1	ENaC	27..632	CDD:273304	116/637 (18%)