Protein Alignment ppk23 and asic4a

DIOPT Version :9

• Sequence 1: NP_001097011.1
• Gene: ppk23 / 32731
• FlyBaseID: FBgn0030844
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_999952.1
• Gene: asic4a / 407668
• ZFINID: ZDB-GENE-040513-5
• Length: 539
• Species: Danio rerio
• Alignment Length: 634
• Identity: 129/634 - (20%)
• Similarity: 228/634 - (35%)
• Gaps: 210/634 - (33%)

  Fly    24 RRSLIYQ-----TKE---FFQNSTLHGVRYIAESGRPIGEKFMWFCFTSIGAVTALVIIMSLWEK 80
            :.|||.:     ||:   |...|:|||:.:|..|||....:.:|    ::..:.:|.:.:....|
Zfish    26 KESLIEESCSPPTKDLAGFASASSLHGINHIFVSGRLGVRQTLW----ALAFLVSLALFLYQAAK 86

  Fly    81 ----FQTNPTITGLDTDFHNQNVVFPTTVVCP------EAAFDHDKTYEKVYNTLANYDEAQAQM 135
                :..:|.:|.|:.: ....:|||...:|.      .|..|.|     :|: |||
Zfish    87 CAISYLEHPHVTALNEE-ATPEMVFPAVTICNINRFRFSALTDAD-----IYH-LAN-------- 136

  Fly   136 YTPFLRILTSLNFENVRDAKVLSQSIP----QNLLDAHTIREWAFEGHIDCKNVFVSCKYRDEDI 196
                   ||.|..:|....|......|    |::.:.        .|| ..:.:..||.:..::.
Zfish   137 -------LTGLPPKNKDGHKPTDLEYPAPDMQDIFNR--------TGH-QLEEMLKSCNFSGQNC 185

  Fly   197 PCCDHFEPIYTEHGFCYAFNSRFKSTPTEDVKTGAPH------DLYETDKKWALFFIP-----NS 250
            ...| |..:||.:|.||.||.. |:|..:..:.|..:      |:.:.|      ::|     |.
Zfish   186 SAED-FTVVYTRYGKCYTFNGN-KTTSRKTKQGGMGNGLEIMLDIQQDD------YLPIWKETNE 242

  Fly   251 TS-----RIFIFSNEEYFGSDFNAQIDWSEPQLVEVRISKKNTYTTDDARQLSIGQRKCIFSDEV 310
            ||     |:.|.|.:|             .|.:.::...            :|.|.:..:...|.
Zfish   243 TSLEAGIRVQIHSQDE-------------PPYIHQLGFG------------VSPGFQTFVSCQEQ 282

  Fly   311 KLNYFP-----------------DAYTFSSCMKQCRMNKAIKLCKCNPPFYKPIRELSCVINIFT 358
            :|.|.|                 |.|:.|:|..:|...:.::.|||.
Zfish   283 RLTYLPQPWGNCRSTSEQMIPGYDTYSISACRLRCETLEVLRECKCR------------------ 329

  Fly   359 NLIAYILLLYLTPKANVPMCSIKDFDCLDEFKSNITNIK-DCLQCELSCSKTVFNID-KLIKMS- 420
                   ::::...||:  |:..|..|:|:..:.:.... |...||..|:.|.:..: .::|:.
Zfish   330 -------MVHMPGDANI--CTPSDIKCVDKALALLQKSSGDTCFCETPCNLTRYGKELSMVKIPS 385

  Fly   421 -----------DRPES--------LGVLVEFLTWPIIRYKREVLFGWVDLLVSFGGIASLFLGFS 466
                       |:.|.        |.:..|.|.:..|..|:  .:....||...||...||:|.|
Zfish   386 KGSARYLSRKYDKSEDYIRDNFLVLDIFFEALNYETIEQKK--AYDVAGLLGDIGGQMGLFIGAS 448

  Fly   467 LLSGVEIIYYFTLRACCMVY---KNRQELYEIEEKIRQEPPPKIDLKLSLKSHNPRIGDTPTSAV 528
            :|:.:||:.|        ||   |:|     :|..:|   |.:.|.|.:.:........|.....
Zfish   449 VLTILEILDY--------VYEVIKHR-----LERLLR---PQRDDKKQTQQQQQASTVATVNLEE 497

  Fly   529 LKVKPAEESAGPNPLGGYQRKHEKDYSLNTKNYYKTPKVVPDYGYTSKT 577
            :|.|.:.|.:         |.|.:....||        ::|::.:..:|
Zfish   498 MKAKDSSEMS---------RSHSEGAYANT--------ILPNHHHHHRT 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk23	NP_001097011.1	ASC	34..476	CDD:279230	104/510 (20%)
asic4a	NP_999952.1	ASC	44..472	CDD:295594	110/537 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	474..494		3/19 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920