Protein Alignment ppk23 and scnn1a

DIOPT Version :9

• Sequence 1: NP_001097011.1
• Gene: ppk23 / 32731
• FlyBaseID: FBgn0030844
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_001184124.1
• Gene: scnn1a / 395013
• XenbaseID: XB-GENE-996083
• Length: 633
• Species: Xenopus tropicalis
• Alignment Length: 724
• Identity: 148/724 - (20%)
• Similarity: 230/724 - (31%)
• Gaps: 259/724 - (35%)

  Fly     1 MPQEKRHPPESRTQRFLETLVIFRRSLIYQTKEFF-QNSTLHG-VRYIAESGRPIGEKFMWFCFT 63
            |.:|.::..|...:.|.....:|         ||| .|:|:|| :|.:              |..
 Frog     1 MSKEVKNEKEPLIEFFSSYRELF---------EFFCSNTTIHGAIRLV--------------CSR 42

  Fly    64 SIGAVTALVIIMSL-------WE------KFQTNPTITGLDTDFHNQNVVFPTTVVCPEAAFDHD 115
            |....||..:::.|       |:      ::.:.|  ..::.:.::..:.||...||....:
 Frog    43 SNRMKTAFWLVLFLATFGLMYWQFGLLFGQYFSYP--VSINLNVNSDKLPFPAVTVCTLNPY--- 102

  Fly   116 KTYEKVYNTLANYD-EAQAQMY-----------------------TPFLRILTSLNFENVRDAKV 156
             .|:.:.|.|...| |.|..:|                       .|.|..|..|.....:..:|
 Frog   103 -RYKAIQNDLQELDKETQRTLYELYKYNSTGVQGWIPTNQRVRRDRPGLPHLLELVPPGSKTHRV 166

  Fly   157 LSQSIPQNL-----------------------------LDAHTIREW----------------AF 176
            ....|.:.|                             :||  ||||                |.
 Frog   167 SRSVIEEELQVKRREWNIGFKLCNETGGDCFYQTYTSGVDA--IREWYRFHYINILARVPEEAAI 229

  Fly   177 EGHIDCKNVFVSCKYRDEDIPCC----DHFEPIYTEHGFCYAFN------SRFKSTPTEDVKTG- 230
            :|. ..:|...:|::.:|.  |.    .||.  :..:|.||.||      |...|:....:|.|
 Frog   230 DGE-QLENFIFACRFNEES--CTKANYSHFH--HAIYGNCYTFNQNRSGQSNLWSSSMPGIKNGL 289

  Fly   231 ------APHDLYETDKKWALFFIPNSTS----RIFIFSNEE-YFGSDFNAQIDWSEPQLVEVRIS 284
                  ..||           :||..:|    |:.:..::| .|..|....|    |..:|..|.
 Frog   290 TLILRTEQHD-----------YIPLLSSVAGARVLVHGHKEPAFMDDSGFNI----PPGMETSIG 339

  Fly   285 -KKNTYTTDDARQLSIGQRKCIFSD--------EVKLNYFPDAYTFSSCMKQCRMNKAIKLCKCN 340
             ||.|......:          :||        :|| |.|...||...|::.|.....::.|.|.
 Frog   340 MKKETVNRMGGK----------YSDCSEDGSDVDVK-NLFESEYTEQVCVRSCFQAAMVERCGCG 393

  Fly   341 PPFY--KPIRELSCVINIFTNL--IAYILLLYLTPKANVPMCSIKDFDCLDEFKSNITNI----- 396
            ..||  .|..|. |..|...:.  ..|.|::                    ||.||....
 Frog   394 YAFYPLSPGDEF-CDYNKHKSWGHCYYKLII--------------------EFTSNKLGCFSKCR 437

  Fly   397 KDCLQCELSCS------------KTVFN-IDKLIKMSDRP--ESLGVLVEFLTWPIIRYKREVLF 446
            |.||..|...:            ..||: :.:...::||.  ..|.:..|.|.:..|:....:
 Frog   438 KPCLVSEYQLTAGYSKWPNRVSQDWVFHTLSRQYNLTDRNGIAKLNIYFEELNYKTIQESPTI-- 500

  Fly   447 GWVDLLVSFGGIASLFLGFSLLSGVEII-----------------YYFTLRACCMVYKNRQELYE 494
            ..|.||...|...||:.|.|:||.||::                 ||         ||...| .|
 Frog   501 NMVMLLSLLGSQWSLWFGSSVLSVVEMLELVIDLVIIVLIMLFHRYY---------YKQADE-GE 555

  Fly   495 IEEKIRQEPPPKIDLKLSLKSHNPRIGDTPTSAVLKV-----KPAEESAGPNPLGGYQRKHEKDY 554
            ....:....|...||:..: .|.|| .|.|...:..|     .||.||.....:|....:.....
 Frog   556 ATSAVPTPAPSFADLEQQV-PHVPR-SDLPQRQISVVADITPPPAYESLDLRSVGALSSRSSSLR 618

  Fly   555 SLNTKNYYK 563
            | ::::||:
 Frog   619 S-SSRSYYE 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk23	NP_001097011.1	ASC	34..476	CDD:279230	119/597 (20%)
scnn1a	NP_001184124.1	ENaC	18..602	CDD:273304	139/680 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010