DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk23 and ppk16

DIOPT Version :9

Sequence 1:	NP_001097011.1	Gene:	ppk23 / 32731	FlyBaseID:	FBgn0030844	Length:	591	Species:	Drosophila melanogaster
Sequence 2:	NP_001334673.1	Gene:	ppk16 / 3885612	FlyBaseID:	FBgn0065108	Length:	531	Species:	Drosophila melanogaster

Alignment Length:	539	Identity:	122/539 - (22%)
Similarity:	229/539 - (42%)	Gaps:	98/539 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 HPPESRTQRFLETLVIFRRSLIYQTKEFFQNSTLHGVRYIAESGRPIGEKFMWFCFTSIGAVTAL 71
            |.|.....||.:....|..::    :.:.|.::|||..||........|::.|.....:..:|::
  Fly    36 HNPIQPQHRFRQIGEWFTENM----RNYCQTTSLHGFSYITRQDISRHERWFWLVVVILAIITSI 96

  Fly    72 VIIMSLWEKFQTNPTITGLDTD-FHNQNVVFPTTVVCPEAAFDHDKTYEKVYNT--LANYDEAQ- 132
            |:::..|...|..||:|.:::. |...|:.||...:|         .:.|:..:  |:..|:.|
  Fly    97 VLVVVSWYWSQETPTVTVIESSHFPTWNIPFPAVTIC---------NFNKISKSKALSLLDQMQV 152

  Fly   133 ------AQMYTPF----LRILTSLNFENVRD-AKVLSQSIPQNLLDAHTIREWAFEGHIDCKNVF 186
                  ::::..|    |.:.|.::.::::. .::||       |:..|:.....:...||..:.
  Fly   153 PVGINRSELHNLFNLTLLPVDTMISNDSLQKYDRILS-------LNNLTLNRLTQQLSPDCIEMI 210

  Fly   187 VSCKYRDEDIPCCDHFEPIYTEHGFCYAFN--SRFKSTPTEDVKTGAPHDLYETDKKWALFFIPN 249
            .||.::..:..|...|:.|.|..|.|..||  ....:...|.:....|...|....    ...|.
  Fly   211 SSCIWKGINTRCESLFQRIDTMEGQCCTFNYFGGISNNFPEKIAYQVPKRPYRVTG----CGYPT 271

  Fly   250 STSRIFIFSNEEYFGSDF-------------NAQIDWSEPQLVE------VRISKKNTYTTDDAR 295
            ..|.:......:|:|:.|             |...:.||.::|.      |||:.::||.|:|.|
  Fly   272 GLSVLLNPMISDYYGTFFSGFGFRLLLHDAYNFPDENSETKVVTTTRESFVRINPESTYATNDIR 336

  Fly   296 QLSIGQRKCIFSDEVKLNYFPDAYTFSSCMKQCRMNKAIKLCKCNPPF------YK--PIRELSC 352
            ::.:..|.|:|..|:.::.. ..|:|.:||.:||:...:.||.|.||:      ||  .:.:.:|
  Fly   337 RMDLSLRNCLFGSEMTMHGL-RRYSFINCMFECRVRMTVDLCGCLPPYVYNNGSYKVCGVLQTNC 400

  Fly   353 VIN---IFTNLIAYILLLYLTPKANVPMCSIKDFD-----CLDEFKSN---ITNIKDCLQCELSC 406
            :|:   :|::.:|.:         |..:..:::.|     ||.:.:||   ..:....|......
  Fly   401 IIHSKRLFSHALANL---------NFSLSIVRETDSFPCGCLPDCQSNHYVSESTTGRLDISYFA 456

  Fly   407 SKTVFNIDKLIKMSDRPESLGVLVEFLTWPIIRYKREVLFGWVDLLVSFGGIASLFLGFSLLSGV 471
            ::..||     ..:||   :.:.|.|......||:.::...|:..|.||||:..|.:|||:::..
  Fly   457 NRPTFN-----NATDR---ILLHVFFSDLMSTRYRTDIFQNWLSALASFGGLLGLIMGFSIVTAF 513

  Fly   472 EIIYYFTLRACCMVYKNRQ 490
            |.||:.|.|. ...|.||:
  Fly   514 EFIYFLTFRP-VFNYINRE 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk23	NP_001097011.1	ASC	34..476	CDD:279230	111/496 (22%)
ppk16	NP_001334673.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910